SPATC1 and MROH5

		SPATC1	MROH5
Description		spermatogenesis and centriole associated 1	maestro heat like repeat family member 5 (gene/pseudogene)
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytoskeleton	Cytoplasm
	Molecular Function
	Biological Process
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Brain morphology (MOSTest) ( 32665545) Fibrinogen levels ( 28107422) Mean corpuscular hemoglobin ( 29403010)	Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder ( 30804558) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Response to antidepressants (symptom improvement) ( 29160301)
Interacting Genes		2 interacting genes: CDC20 TUBG1	1 interacting genes: ASGR2
Entrez ID		375686	389690
HPRD ID		15433	13480
Ensembl ID		ENSG00000186583	ENSG00000226807
Uniprot IDs		A0A140VJV4 Q76KD6	Q6ZMW9 Q6ZUA9
PDB IDs
Enriched GO Terms of Interacting Partners?		Mitotic Spindle Organization Microtubule Cytoskeleton Organization Involved In Mitosis Metaphase/anaphase Transition Of Meiosis I Spindle Organization Microtubule Nucleator Activity Meiotic Cell Cycle Phase Transition Mitotic Checkpoint Complex Positive Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Spindle Polar Microtubule Regulation Of Anaphase-promoting Complex-dependent Catabolic Process Positive Regulation Of Ubiquitin Protein Ligase Activity Chromosome Organization Positive Regulation Of Synapse Maturation Metaphase/anaphase Transition Of Cell Cycle Anaphase-promoting Complex Binding Ubiquitin-protein Transferase Activator Activity Positive Regulation Of Synaptic Plasticity Ubiquitin Ligase Activator Activity Microtubule Cytoskeleton Organization Gamma-tubulin Ring Complex Gamma-tubulin Complex Positive Regulation Of Ubiquitin-protein Transferase Activity Mitotic Spindle Microtubule Mitotic Sister Chromatid Cohesion Positive Regulation Of Mitotic Metaphase/anaphase Transition Anaphase-promoting Complex-dependent Catabolic Process Positive Regulation Of Mitotic Sister Chromatid Separation Anaphase-promoting Complex Meiotic Spindle Organization Pericentriolar Material Mitotic Spindle Assembly Checkpoint Signaling Negative Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Meiotic Nuclear Division Centrosome Positive Regulation Of Chromosome Separation Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Synapse Maturation Microtubule Nucleation Non-motile Cilium Microtubule-based Process Mitotic Sister Chromatid Segregation Negative Regulation Of Mitotic Nuclear Division Sister Chromatid Segregation Sister Chromatid Cohesion Spindle Microtubule Mitotic Spindle Assembly Positive Regulation Of Mitotic Nuclear Division Condensed Nuclear Chromosome G2/M Transition Of Mitotic Cell Cycle	Asialoglycoprotein Receptor Activity Fucose Binding D-mannose Binding Endoplasmic Reticulum Quality Control Compartment Pattern Recognition Receptor Activity
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