TMPRSS11A and ZBTB17

Number of citations of the paper that reports this interaction (PMID 15095404)
3

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		TMPRSS11A	ZBTB17
Gene Name		transmembrane protease, serine 11A	zinc finger and BTB domain containing 17
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Integral Component Of Plasma Membrane	Nucleoplasm
	Molecular Function	Serine-type Endopeptidase Activity	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Metal Ion Binding
	Biological Process	Proteolysis Cell Cycle	Gastrulation With Mouth Forming Second Transcription, DNA-templated Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Ectoderm Development Endoplasmic Reticulum Unfolded Protein Response Cellular Protein Metabolic Process Negative Regulation Of Cell Cycle Positive Regulation Of Transcription, DNA-templated
Pathways			IRE1alpha activates chaperones XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS			Dilated cardiomyopathy ( 21459883)
Protein-Protein Interactions		1 interactors: ZBTB17	19 interactors: CDKN2B CREBBP DIS3 DNMT3A EP300 ESR1 ESR2 GTF2I HCFC1 HK2 HK3 IRF8 ITGB5 MAX MSX2 MYC PGR TMPRSS11A TOPBP1
Entrez ID		339967	7709
HPRD ID		07123	04968
Ensembl ID		ENSG00000187054	ENSG00000116809
Uniprot IDs		A8KA85 B5MDI9 Q6ZMR5	Q13105
PDB IDs			2LVR 2LVT 2LVU 2M0D 2M0E 2M0F 2Q81 3M52
Enriched GO Terms of Interacting Partners?			Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Negative Regulation Of Gene Expression Gene Expression Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Cellular Response To Organic Substance Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Response To Organic Substance Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Gland Development N-terminal Peptidyl-lysine Acetylation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Rhythmic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Chromatin Modification Multicellular Organismal Development Gland Morphogenesis Branching Involved In Mammary Gland Duct Morphogenesis Regulation Of Gene Expression Anatomical Structure Development Mammary Gland Development Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Steroid Hormone Stimulus Positive Regulation Of Gene Expression Negative Regulation Of Cellular Metabolic Process Chromatin Organization Cellular Response To Lipid Positive Regulation Of Cellular Biosynthetic Process Mammary Gland Duct Morphogenesis Branching Morphogenesis Of An Epithelial Tube Mammary Gland Branching Involved In Pregnancy See more
Tagcloud ?			10k 1p35 1p36 aboriginal affymetrix annotated arrangements cataract descent dysmorphism encompasses epha2 ephb2 erythematous harbour lod merlin monosomy overlaps pedigree penetrant positional rash rs1441834 rs966321 ruled segregating spans volkmann
Tagcloud (Difference) ?			10k 1p35 1p36 aboriginal affymetrix annotated arrangements cataract descent dysmorphism encompasses epha2 ephb2 erythematous harbour lod merlin monosomy overlaps pedigree penetrant positional rash rs1441834 rs966321 ruled segregating spans volkmann
Tagcloud (Intersection) ?