KRTAP19-2 and SLC15A3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KRTAP19-2	SLC15A3
Description		keratin associated protein 19-2	solute carrier family 15 member 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Intermediate Filament	Lysosome Lysosomal Membrane Endosome Endosome Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding Symporter Activity Peptide:proton Symporter Activity Peptidoglycan Transmembrane Transporter Activity Transmembrane Transporter Activity Dipeptide Transmembrane Transporter Activity
	Biological Process		Immune System Process Monoatomic Ion Transport Protein Transport Peptide Transport Peptidoglycan Transport Innate Immune Response Transmembrane Transport Positive Regulation Of Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Dipeptide Import Across Plasma Membrane Proton Transmembrane Transport
Pathways		Keratinization	Proton/oligopeptide cotransporters
Drugs
Diseases
GWAS			Refractive error ( 32231278) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		46 interacting genes: ADAMTSL4 ANAPC11 ATN1 C11orf16 CHRD COL8A1 CREB5 CYSRT1 EFEMP1 ETHE1 FBLN1 FOXD2 FOXH1 GNE HOXC8 HSD3B7 KPRP KRTAP12-2 KRTAP12-4 KRTAP3-3 KRTAP4-12 KRTAP6-3 KRTAP9-3 LCE2D MEIS2 MGAT5B MKRN3 NTAQ1 OLIG3 OTX1 PCSK5 PIGS POU4F2 RHBG SLC12A4 SLC15A3 SMARCC1 SNRPC SPAG8 TEKT4 TENT5D TFAP2D VENTX VGLL3 VWC2L ZIC1	13 interacting genes: CALCOCO2 GMCL1 HOXA1 KRT31 KRTAP10-3 KRTAP12-2 KRTAP19-2 KRTAP5-9 KRTAP9-8 LZTS2 MDFI TRIM27 VKORC1
Entrez ID		337969	51296
HPRD ID		11206	11565
Ensembl ID		ENSG00000186965	ENSG00000110446
Uniprot IDs		Q3LHN2	A0A7P0T8H0 Q8IY34
PDB IDs			8WX2
Enriched GO Terms of Interacting Partners?		Intermediate Filament DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Pattern Specification Process Sequence-specific Double-stranded DNA Binding Protein Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription DNA-binding Transcription Factor Activity Positive Regulation Of Transcription By RNA Polymerase II	Intermediate Filament Keratin Filament Semicircular Canal Formation Abducens Nerve Formation Optokinetic Behavior Peptidyl-glutamic Acid Carboxylation Oxidoreductase Activity, Acting On CH Or CH2 Groups, Disulfide As Acceptor Vitamin-K-epoxide Reductase (warfarin-insensitive) Activity Vitamin-K-epoxide Reductase (warfarin-sensitive) Activity Primary Ureteric Bud Growth
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