C14orf39 and MT1X

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		C14orf39	MT1X
Description		chromosome 14 open reading frame 39	metallothionein 1X
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Central Element Chromosome	Nucleus Cytoplasm
	Molecular Function	Protein Binding	Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	DNA Recombination Homologous Chromosome Pairing At Meiosis Synaptonemal Complex Assembly Spermatogenesis Meiotic DNA Double-strand Break Processing Involved In Reciprocal Meiotic Recombination Cell Differentiation Oogenesis Regulation Of DNA-binding Transcription Factor Activity Meiotic Cell Cycle	Intracellular Zinc Ion Homeostasis Response To Metal Ion Detoxification Of Copper Ion Cellular Response To Erythropoietin Negative Regulation Of Growth Cellular Response To Cadmium Ion Cellular Response To Copper Ion Cellular Response To Zinc Ion
Pathways			Metallothioneins bind metals
Drugs			Silver
Diseases
GWAS		A body shape index ( 34021172) Chronotype ( 30696823) Glaucoma ( 30054594) Glaucoma (high intraocular pressure) ( 33627673) Glaucoma (low intraocular pressure) ( 33627673) Glaucoma (primary open-angle) ( 33627673) Gut microbiota (bacterial taxa) ( 27723756) Heel bone mineral density ( 30598549) Height ( 25282103 23563607 28552196) Hip circumference adjusted for BMI ( 34021172 28552196) Macular thickness ( 30535121) Menarche (age at onset) ( 27182965) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Anti-chlamydia trachomatis IgG seropositivity ( 29967566) Apolipoprotein A1 levels ( 32203549) Gambling ( 22780124)
Interacting Genes		4 interacting genes: HPGDS MT1X TEAD2 TRIM54	5 interacting genes: C14orf39 POT1 TERF1 TERF2IP VKORC1
Entrez ID		317761	4501
HPRD ID		08504	01130
Ensembl ID		ENSG00000179008	ENSG00000187193
Uniprot IDs		Q8N1H7	A0A140VJP8 P80297
PDB IDs
Enriched GO Terms of Interacting Partners?			Shelterin Complex Nuclear Telomere Cap Complex G-rich Strand Telomeric DNA Binding Telomere Capping Telomere Maintenance Via Telomerase RNA-templated DNA Biosynthetic Process Telomeric DNA Binding Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Telomere Maintenance Positive Regulation Of Telomere Maintenance Chromosome Organization Negative Regulation Of Chromosome Organization DNA Biosynthetic Process Telomere Maintenance Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Telomeric D-loop Disassembly Telomeric Loop Disassembly Telomere Organization Negative Regulation Of DNA Metabolic Process Chromosome, Telomeric Region Chromosome Negative Regulation Of Telomere Maintenance Via Telomerase DNA Metabolic Process Regulation Of Chromosome Organization Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process Positive Regulation Of DNA Metabolic Process Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Via Telomere Lengthening Chromosome Organization Involved In Meiotic Cell Cycle Regulation Of DNA Metabolic Process Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Regulation Of DNA Biosynthetic Process Positive Regulation Of Shelterin Complex Assembly Positive Regulation Of Organelle Organization Positive Regulation Of DNA Strand Elongation Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Vitamin-K-epoxide Reductase (warfarin-insensitive) Activity Negative Regulation Of Telomeric D-loop Disassembly Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Positive Regulation Of Telomeric Loop Disassembly Negative Regulation Of DNA Recombination At Telomere Peptidyl-glutamic Acid Carboxylation Oxidoreductase Activity, Acting On CH Or CH2 Groups, Disulfide As Acceptor Vitamin-K-epoxide Reductase (warfarin-sensitive) Activity Meiotic DNA Double-strand Break Processing Involved In Reciprocal Meiotic Recombination
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?