TMOD4 and SLAMF7

		TMOD4	SLAMF7
Description		tropomodulin 4	SLAM family member 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Striated Muscle Thin Filament Myofibril	Plasma Membrane External Side Of Plasma Membrane Membrane
	Molecular Function	Actin Binding Protein Binding Tropomyosin Binding	Identical Protein Binding
	Biological Process	Muscle Contraction Actin Filament Organization Myofibril Assembly Pointed-end Actin Filament Capping	Adaptive Immune Response Immune System Process Immune Response Cell Adhesion Natural Killer Cell Activation T Cell Activation Natural Killer Cell Mediated Cytotoxicity Innate Immune Response
Pathways		Striated Muscle Contraction	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs			Elotuzumab
Diseases
GWAS		Chronic kidney disease ( 30226566) Coronary artery disease ( 30402224) Hypertension ( 30226566) Ischemic stroke ( 29930801) Myocardial infarction ( 30226566)	Blood protein levels ( 30072576) IgM levels ( 28628107) Inflammatory bowel disease ( 23128233) Microalbuminuria ( 26631737) Multiple sclerosis ( 24076602)
Interacting Genes		4 interacting genes: APP IDH1 NEB TXN2	4 interacting genes: CLK3 MAK SH2D1A TRIB2
Entrez ID		29765	57823
HPRD ID		16164	09432
Ensembl ID		ENSG00000163157	ENSG00000026751
Uniprot IDs		Q9NZQ9	B4DVL7 B4DW98 Q9NQ25
PDB IDs
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Supramolecular Fiber Organization Glyoxylate Cycle Isocitrate Dehydrogenase (NADP+) Activity Cardiac Muscle Thin Filament Assembly Myofibril Cortical Microtubule Plus-end Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Supramolecular Fiber Organization Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Isocitrate Metabolic Process Somatic Muscle Development Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Regulation Of Phospholipid Catabolic Process Heparan Sulfate Binding Signaling Receptor Activator Activity Glyoxylate Metabolic Process Positive Regulation Of Microtubule Nucleation	Cytoplasm Negative Regulation Of Uterine Smooth Muscle Contraction Alpha-1B Adrenergic Receptor Binding Alpha-2C Adrenergic Receptor Binding Phospholipase C-activating Adrenergic Receptor Signaling Pathway Protein Homodimerization Activity Adenylate Cyclase-inhibiting Adrenergic Receptor Signaling Pathway Protein Phosphorylation Negative Regulation Of Non-motile Cilium Assembly Skeletal Muscle Tissue Development Left Lung Morphogenesis Superior Vena Cava Morphogenesis Prolactin Secreting Cell Differentiation Cell Proliferation Involved In Outflow Tract Morphogenesis Pulmonary Vein Morphogenesis Subthalamic Nucleus Development Regulation Of Actin Filament Depolymerization Actin Filament Capping Negative Regulation Of Protein-containing Complex Disassembly Negative Regulation Of Actin Filament Depolymerization Negative Regulation Of Actin Filament Polymerization Pantothenate Kinase Activity Regulation Of Protein Depolymerization Actin Filament-based Process Alpha2-adrenergic Receptor Activity Phosphorylation Pulmonary Myocardium Development Endodermal Digestive Tract Morphogenesis Deltoid Tuberosity Development Norepinephrine Binding Thermoception Somatotropin Secreting Cell Differentiation Cell Proliferation Involved In Heart Morphogenesis Acetyl-CoA Binding Negative Regulation Of Norepinephrine Secretion Epinephrine Binding Negative Regulation Of Epinephrine Secretion Protein Kinase Activity Striated Muscle Tissue Development Embryonic Heart Tube Left/right Pattern Formation Muscle Structure Development Extraocular Skeletal Muscle Development Atrioventricular Valve Development Regulation Of Actin Filament Polymerization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Protein-containing Complex Disassembly Negative Regulation Of Protein-containing Complex Assembly Ubiquitin-protein Transferase Regulator Activity Pointed-end Actin Filament Capping
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