NBPF22P and RGP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		NBPF22P	RGP1
Description		NBPF member 22, pseudogene	RGP1 partner of RAB6A GEF complex
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Golgi Membrane Cytoplasm Cytosol Plasma Membrane Membrane Trans-Golgi Network Membrane Protein-containing Complex Ric1-Rgp1 Guanyl-nucleotide Exchange Factor Complex
	Molecular Function		Guanyl-nucleotide Exchange Factor Activity Protein Binding Small GTPase Binding
	Biological Process		Retrograde Transport, Endosome To Golgi Negative Regulation Of Protein Catabolic Process Positive Regulation Of GTPase Activity
Pathways			Intra-Golgi traffic Retrograde transport at the Trans-Golgi-Network RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Attention function in attention deficit hyperactive disorder ( 26174813) Daytime sleep phenotypes ( 27126917) Initial pursuit acceleration ( 29064472) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661)	Brain morphology (MOSTest) ( 32665545) Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		6 interacting genes: AQP1 ENKD1 LMO3 PARVG RGP1 SMARCE1	2 interacting genes: NBPF22P RFPL3
Entrez ID		285622	9827
HPRD ID			13790
Ensembl ID			ENSG00000107185
Uniprot IDs			A8K0K1 Q92546
PDB IDs
Enriched GO Terms of Interacting Partners?		Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Nitric Oxide Transmembrane Transporter Activity Metanephric Proximal Convoluted Tubule Segment 2 Development Metanephric Glomerulus Vasculature Development Glycerol Transmembrane Transporter Activity Corticotropin Secretion Ric1-Rgp1 Guanyl-nucleotide Exchange Factor Complex Positive Regulation Of Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Nitric Oxide Transport Establishment Or Maintenance Of Actin Cytoskeleton Polarity Cerebrospinal Fluid Secretion Carbon Dioxide Transmembrane Transporter Activity Positive Regulation Of Saliva Secretion Water Transmembrane Transporter Activity Cellular Response To Mercury Ion Transepithelial Water Transport Hydrogen Peroxide Transmembrane Transport Hydrogen Peroxide Channel Activity Potassium Ion Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Lipid Digestion Establishment Or Maintenance Of Cell Polarity Pancreatic Juice Secretion Establishment Or Maintenance Of Cell Polarity Regulating Cell Shape Renal Water Absorption Glomerulus Vasculature Development Intracellularly CGMP-activated Cation Channel Activity Ankyrin-1 Complex Glycerol Transmembrane Transport Intracellular Water Homeostasis Ammonium Transmembrane Transport Ammonium Channel Activity Polyol Transmembrane Transport Renal Water Transport Cytoskeleton Organization Cellular Response To Salt Stress Response To Mercury Ion Regulation Of Saliva Secretion BBAF Complex Positive Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway 9+0 Non-motile Cilium Transcription Coactivator Activity Positive Regulation Of Digestive System Process Epithelial Fluid Transport Water Channel Activity Metanephric Tubule Development Metanephric Nephron Tubule Development Regulation Of Developmental Process Lateral Ventricle Development
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