WDR62 and ZNF540

		WDR62	ZNF540
Description		WD repeat domain 62	zinc finger protein 540
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleus Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Centriolar Satellite	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding	MRNA Regulatory Element Binding Translation Repressor Activity RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Positive Regulation Of Neuroblast Proliferation Mitotic Spindle Organization Centriole Replication Nervous System Development Cerebral Cortex Development Neurogenesis Regulation Of Neuron Differentiation Regulation Of Centrosome Cycle Positive Regulation Of Neuron Migration	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Gene Expression Negative Regulation Of Translation Negative Regulation Of DNA-templated Transcription
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS			Refractive error ( 32231278)
Interacting Genes		10 interacting genes: DYRK2 ENKD1 LRIF1 MAGEB4 MAPK8 MAPK9 P4HA3 RALY TBC1D23 TBP
Entrez ID		284403	163255
HPRD ID		10721	15827
Ensembl ID		ENSG00000075702	ENSG00000171817
Uniprot IDs		A0A7P0T9D9 A0A7P0TAK3 A0A7P0Z436 O43379	Q8NDQ6
PDB IDs
Enriched GO Terms of Interacting Partners?		JUN Kinase Activity Regulation Of RNA Metabolic Process MAP Kinase Activity Regulation Of Nucleobase-containing Compound Metabolic Process Fc-epsilon Receptor Signaling Pathway Protein Serine/threonine/tyrosine Kinase Activity Nucleus Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process JUN Phosphorylation	Regulation Of Centrosome Cycle Regulation Of Neuroblast Proliferation Positive Regulation Of Neuron Migration Centriole Assembly Positive Regulation Of Neural Precursor Cell Proliferation Centriole Replication Positive Regulation Of Neuroblast Proliferation Regulation Of Neuron Migration Cerebral Cortex Development Microtubule Organizing Center Organization Regulation Of Neural Precursor Cell Proliferation Mitotic Spindle Organization Neurogenesis Centriolar Satellite Microtubule Cytoskeleton Organization Involved In Mitosis Centriole Spindle Organization Spindle Pole Regulation Of Neuron Differentiation Positive Regulation Of Neurogenesis
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