GNRH2 and GNRHR2

Number of citations of the paper that reports this interaction (PMID 11889221)
16

Data Source:
HPRD (in vivo)

		GNRH2	GNRHR2
Gene Name		gonadotropin-releasing hormone 2	gonadotropin-releasing hormone (type 2) receptor 2, pseudogene
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Hormone Activity	Gonadotropin-releasing Hormone Receptor Activity Peptide Binding
	Biological Process	Signal Transduction Multicellular Organismal Development	G-protein Coupled Receptor Signaling Pathway Cellular Response To Gonadotropin-releasing Hormone
Pathways		G alpha (q) signalling events G alpha (q) signalling events Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) Hormone ligand-binding receptors Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs			Gonadorelin Nafarelin Danazol
Diseases
GWAS
Protein-Protein Interactions		2 interactors: APP GNRHR2	1 interactors: GNRH2
Entrez ID		2797	114814
HPRD ID		03830	11780
Ensembl ID		ENSG00000125787
Uniprot IDs		O43555
PDB IDs
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Cellular Response To Gonadotropin-releasing Hormone Neuron Remodeling Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Neuron Recognition RNA Polyadenylation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Neuron Apoptotic Process Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Visual Behavior Neuron Death Platelet Degranulation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neuromuscular Process Controlling Balance Synapse Assembly MRNA 3'-end Processing Regulation Of ERBB Signaling Pathway Associative Learning Developmental Cell Growth Regulation Of Synapse Structure Or Activity Feeding Behavior Regulation Of Multicellular Organism Growth
Tagcloud ?		axes chem crh cyp11a1 cyp11b cyp19a1a eleutheroembryos environ esr1 fertilization fshb gnrh3 gonadal gonadogenesis hpa hpf hpg hsd11b2 hsd17b3 hypothalamic lhb norgestrel pomc pose setac star toxicol vtg1 zebrafish	17betahsd 5mg atretic commonalities cyp17a1 cyp19a cyp19b dehp ethylhexyl fshbeta gonad hatching hpg ldlr medaka mehhp mehp melastigma meohp oryzias ovaries phthalate reproduction spawned spawning star testes vitellogenin vtg
Tagcloud (Difference) ?		axes chem crh cyp11a1 cyp11b cyp19a1a eleutheroembryos environ esr1 fertilization fshb gnrh3 gonadal gonadogenesis hpa hpf hsd11b2 hsd17b3 hypothalamic lhb norgestrel pomc pose setac toxicol vtg1 zebrafish	17betahsd 5mg atretic commonalities cyp17a1 cyp19a cyp19b dehp ethylhexyl fshbeta gonad hatching ldlr medaka mehhp mehp melastigma meohp oryzias ovaries phthalate reproduction spawned spawning testes vitellogenin vtg
Tagcloud (Intersection) ?		hpg star