GHITM and KLLN

		GHITM	KLLN
Description		growth hormone inducible transmembrane protein	killin, p53 regulated DNA replication inhibitor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Endoplasmic Reticulum Membrane Membrane Mitochondrial Membrane Extracellular Exosome	Nucleus Nucleoplasm Nucleolus
	Molecular Function	Calcium Channel Activity Protein Binding Calcium:proton Antiporter Activity	DNA Binding
	Biological Process	Calcium Ion Transport Mitochondrial Calcium Ion Transmembrane Transport Apoptotic Process Inner Mitochondrial Membrane Organization Negative Regulation Of Release Of Cytochrome C From Mitochondria Calcium Export From The Mitochondrion Mitochondrial Potassium Ion Transmembrane Transport Proton Transmembrane Transport Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport	Apoptotic Process
Pathways
Drugs
Diseases
GWAS		Abstraction and mental flexibility ( 31596458) Influenza A (H1N1) infection ( 26379185) Metabolite levels ( 23823483) Mild influenza (H1N1) infection ( 26379185) Refractive error ( 32231278)	Psoriasis ( 28537254)
Interacting Genes		13 interacting genes: AGTR1 CCR4 DRD2 FAM209A FXYD3 GPR35 GPR37 HTR2C HTR4 JSRP1 PGRMC2 SLC22A1 TMEM242
Entrez ID		27069	100144748
HPRD ID		17038	19461
Ensembl ID		ENSG00000165678	ENSG00000227268
Uniprot IDs		Q9H3K2	B2CW77
PDB IDs
Enriched GO Terms of Interacting Partners?		G Protein-coupled Receptor Activity G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Renal Sodium Excretion Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Sequestering Of Calcium Ion Catecholamine Uptake Dopamine Uptake Serotonin Binding Serotonin Receptor Signaling Pathway Serotonin Receptor Activity Monoatomic Cation Transport G Protein-coupled Serotonin Receptor Activity Interneuron Migration Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Calcium Ion Transmembrane Import Into Cytosol Set1C/COMPASS Complex Neurotransmitter Receptor Activity Dopamine Transport Neurotransmitter Reuptake Monoatomic Ion Transport G Protein-coupled Serotonin Receptor Signaling Pathway Chemokine Receptor Activity Metal Ion Transport Regulation Of Appetite Regulation Of Sequestering Of Calcium Ion Monoamine Transport Neurotransmitter Uptake Dopamine Metabolic Process Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Monoatomic Ion Transmembrane Transport Angiotensin Type I Receptor Activity Calcium Ion Transmembrane Transport Catecholamine Metabolic Process Large Intestinal Transit Dendrite Membrane G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Intracellular Signaling Cassette Bradykinin Receptor Binding G Protein-coupled Receptor Complex Positive Regulation Of Glial Cell-derived Neurotrophic Factor Production Calcium Ion Transport Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Prosaposin Receptor Activity 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine Binding (R)-carnitine Transmembrane Transport Pyrimidine Nucleoside Transmembrane Transporter Activity (R)-carnitine Transmembrane Transporter Activity	Calcium:proton Antiporter Activity Mitochondrial Potassium Ion Transmembrane Transport Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport Calcium Export From The Mitochondrion Negative Regulation Of Release Of Cytochrome C From Mitochondria Mitochondrial Calcium Ion Transmembrane Transport Inner Mitochondrial Membrane Organization Regulation Of Release Of Cytochrome C From Mitochondria Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Sequestering Of Calcium Ion Calcium Ion Transmembrane Import Into Cytosol Calcium Channel Activity Regulation Of Mitochondrion Organization Mitochondrial Membrane Organization Regulation Of Sequestering Of Calcium Ion Regulation Of Generation Of Precursor Metabolites And Energy Potassium Ion Transmembrane Transport Potassium Ion Transport Proton Transmembrane Transport Mitochondrial Membrane Calcium Ion Transmembrane Transport Negative Regulation Of Apoptotic Signaling Pathway Calcium Ion Transport Mitochondrion Organization
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