GFER and METTL9

		GFER	METTL9
Description		growth factor, augmenter of liver regeneration	methyltransferase 9, His-X-His N1(pi)-histidine
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GO Annotations	Cellular Component	Extracellular Region Cytoplasm Mitochondrion Mitochondrial Intermembrane Space Cytosol	Mitochondrion Endoplasmic Reticulum
	Molecular Function	Protein Binding Growth Factor Activity Protein-disulfide Reductase Activity Oxidoreductase Activity Flavin-dependent Sulfhydryl Oxidase Activity Thiol Oxidase Activity Flavin Adenine Dinucleotide Binding	Protein Binding Methyltransferase Activity Transferase Activity Protein-L-histidine N-pros-methyltransferase Activity
	Biological Process	Liver Development Signal Transduction Mitochondrial Disulfide Relay System	Methylation
Pathways		Mitochondrial protein import
Drugs		Flavin adenine dinucleotide
Diseases
GWAS			Schizophrenia, bipolar disorder or recurrent major depressive disorder ( 34099189) Serum immune biomarker levels ( 32066700) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355)
Interacting Genes		8 interacting genes: ASCC2 BNIPL COPS2 COPS5 PLEKHF2 SMAD2 TXN YY1	3 interacting genes: CHMP6 CHRM4 MYG1
Entrez ID		2671	51108
HPRD ID		02954	16839
Ensembl ID		ENSG00000127554	ENSG00000197006
Uniprot IDs		P55789	Q9H1A3
PDB IDs		3MBG 3O55 3TK0 3U2L 3U2M 3U5S 4LDK	7Y9C 7YF2 7YF3 7YF4 8GZE 8GZF
Enriched GO Terms of Interacting Partners?		Protein Deneddylation Protein Neddylation Regulation Of Protein Neddylation COP9 Signalosome SMAD Binding Oxidoreductase Activity, Acting On Metal Ions, NAD Or NADP As Acceptor [methionine Synthase] Reductase (NADPH) Activity Protein-L-histidine N-pros-methyltransferase Activity	ESCRT III Complex Assembly G Protein-coupled Acetylcholine Receptor Activity Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway G Protein-coupled Acetylcholine Receptor Signaling Pathway Flavin-dependent Sulfhydryl Oxidase Activity Thiol Oxidase Activity Mitochondrial Disulfide Relay System Protein-disulfide Reductase Activity Locomotory Exploration Behavior Exploration Behavior 3'-5'-RNA Exonuclease Activity Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Negative Regulation Of Peptidyl-tyrosine Phosphorylation Plasma Membrane Repair Mitotic Cytokinetic Process ESCRT III Complex Regulation Of Signaling Receptor Activity Multivesicular Body Membrane Viral Budding From Plasma Membrane Negative Regulation Of Signaling Receptor Activity Multivesicular Body Organization Amphisome Membrane Late Endosome To Lysosome Transport Lysosomal Membrane Organization Vesicle Fusion With Vacuole Kinetochore Microtubule Viral Budding Regulation Of Exosomal Secretion Negative Regulation Of ERBB Signaling Pathway Vesicle Budding From Membrane Nuclear Membrane Reassembly Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly Viral Release From Host Cell Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Protein Tyrosine Kinase Activity Multivesicular Body Assembly Midbody Abscission Regulation Of Spindle Assembly Multivesicular Body-lysosome Fusion Regulation Of Protein Tyrosine Kinase Activity Late Endosome To Vacuole Transport Cytokinetic Process Acetylcholine Receptor Signaling Pathway Mitochondrial RNA Metabolic Process Membrane Fission Regulation Of Mitotic Spindle Organization Endosome Transport Via Multivesicular Body Sorting Pathway
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