TIMM8B and TAGLN

Data Source: HiPPIP (Novel)

		TIMM8B	TAGLN
Name		translocase of inner mitochondrial membrane 8 homolog B	transgelin
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Mitochondrion Mitochondrial Inner Membrane Mitochondrial Intermembrane Space Membrane Mitochondrial Intermembrane Space Chaperone Complex	Cytoplasm
	Molecular Function	Zinc Ion Binding Metal Ion Binding Protein Transporter Activity	Actin Binding Protein Binding
	Biological Process	Protein Targeting To Mitochondrion Sensory Perception Of Sound Protein Transport Protein Insertion Into Mitochondrial Inner Membrane	Muscle Organ Development Epithelial Cell Differentiation
Pathways		Mitochondrial protein import	None
Drugs		None	Artenimol
GWAS		No GWAS studies recorded	Apolipoprotein B levels ( 32203549 ) Breast cancer in childhood cancer survivors treated with more than 10 gray radiotherapy ( 29059430 ) Medication use (calcium channel blockers) ( 31015401 ) Refractive error ( 32231278 )
Interacting Genes		2 interacting genes: EGFL8 HADHB	9 interacting genes: ACD ACTA1 GORASP2 PIK3CD POT1 PRKCD RNF14 TINF2 USP1
Entrez ID		26521	6876
HPRD ID		16228	02891
Ensembl ID		ENSG00000150779	ENSG00000149591
Uniprot IDs		G3XAN8 Q9Y5J9	Q01995 Q5U0D2
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Acetyl-CoA C-acetyltransferase Activity Acetyl-CoA C-myristoyltransferase Activity Mitochondrial Fatty Acid Beta-oxidation Multienzyme Complex Enoyl-CoA Hydratase Activity (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity Acetyl-CoA C-acyltransferase Activity Meiotic Sister Chromatid Cohesion, Centromeric Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Meiotic Sister Chromatid Cohesion	Telomere Assembly Shelterin Complex Nuclear Telomere Cap Complex Telomere Capping Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of DNA Metabolic Process Telomeric DNA Binding Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Via Telomere Lengthening Telomerase Inhibitor Activity Establishment Of Protein Localization To Telomere Regulation Of DNA Metabolic Process Positive Regulation Of Telomere Maintenance Negative Regulation Of Chromosome Organization Protein Localization To Chromosome, Telomeric Region Positive Regulation Of Macromolecule Metabolic Process Telomere Maintenance Positive Regulation Of Chromosome Organization Regulation Of Telomere Maintenance Positive Regulation Of Metabolic Process Telomere Organization Negative Regulation Of DNA Metabolic Process Telomere Maintenance Via Telomerase RNA-templated DNA Biosynthetic Process Telomere Maintenance Via Telomere Lengthening Chromosome, Telomeric Region Positive Regulation Of Organelle Organization Positive Regulation Of DNA Biosynthetic Process Granulocyte Macrophage Colony-stimulating Factor Receptor Binding Positive Regulation Of Phospholipid Scramblase Activity Positive Regulation Of Glucosylceramide Catabolic Process Positive Regulation Of Error-prone Translesion Synthesis Positive Regulation Of DNA Strand Elongation Regulation Of Chromosome Organization Positive Regulation Of Telomeric D-loop Disassembly G-rich Single-stranded DNA Binding Positive Regulation Of Biosynthetic Process Regulation Of Organelle Organization Regulation Of Macromolecule Biosynthetic Process Cell Surface Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Cellular Component Organization Cell Surface Receptor Signaling Pathway Via STAT Positive Regulation Of Sphingomyelin Catabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process DNA Metabolic Process Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway