GCNT2 and FNDC9

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GCNT2	FNDC9
Description		glucosaminyl (N-acetyl) transferase 2 (I blood group)	fibronectin type III domain containing 9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane	Membrane
	Molecular Function	Protein Binding N-acetyllactosaminide Beta-1,6-N-acetylglucosaminyltransferase Activity UDP-glycosyltransferase Activity Acetylglucosaminyltransferase Activity Transferase Activity Glycosyltransferase Activity	Protein Binding
	Biological Process	Glycosaminoglycan Biosynthetic Process Protein Glycosylation Transforming Growth Factor Beta Receptor Signaling Pathway Multicellular Organism Development Positive Regulation Of Cell Population Proliferation Glycoprotein Biosynthetic Process Post-transcriptional Regulation Of Gene Expression Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Cell-substrate Adhesion Positive Regulation Of Cell Migration Positive Regulation Of Heterotypic Cell-cell Adhesion Maintenance Of Lens Transparency Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of ERK1 And ERK2 Cascade
Pathways
Drugs
Diseases		Adult i phenotype
GWAS		Lean body mass ( 28552196) Lymphocyte count ( 32888494) Monocyte count ( 27863252 32888494) Monocyte percentage of white cells ( 27863252 32888494) Perceived intensity of glucose ( 31005972) Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261) White blood cell count ( 32888494)	Asthma ( 31959851)
Interacting Genes		1 interacting genes: FNDC9	88 interacting genes: ADIPOQ AGTRAP AIG1 AOC3 AQP1 ASGR1 ATXN1 BMP10 C1QL4 C3orf52 CLDN1 CLDN11 CLDN19 CLEC1A CLEC2D CLEC7A CLN6 CLRN2 CMTM5 CNIH3 COL8A2 CTSA CXCL16 CXCL9 CYB5B DEFB132 DOLK EDDM3B EMP3 ENTPD3 ERMP1 EXTL1 GALNT15 GCNT2 HHATL IGFBP5 ITM2A ITM2C JAGN1 KRTCAP3 LHFPL5 LPAR3 MAL MALL MOSPD3 NINJ1 NINJ2 NKG7 NSG1 OLFM4 PGA4 PGAP2 PLLP PLN PLP1 PLP2 PLPP6 PROKR2 RPRM SEC22B SERP2 SFTPC SLC35A1 SLC41A2 SMIM1 SMIM3 ST6GAL2 STX8 TMEM100 TMEM140 TMEM182 TMEM254 TMEM60 TMEM79 TMEM86A TMPRSS4 TNF TRARG1 TREX1 TSPO2 TWSG1 UBIAD1 UPK1B UPK2 VAMP5 VSTM1 ZDHHC22 ZFPL1
Entrez ID		2651	408263
HPRD ID		02695	17524
Ensembl ID		ENSG00000111846	ENSG00000172568
Uniprot IDs		Q8N0V5	Q8TBE3
PDB IDs
Enriched GO Terms of Interacting Partners?			Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Structural Constituent Of Myelin Sheath Plasma Membrane Protein Binding Positive Regulation Of Neutrophil Activation Golgi Apparatus Axon Ensheathment Cytokine Activity Membrane Destabilizing Activity Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Protein Localization To Cell Periphery
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