LINC01558 and CEP43

		LINC01558	CEP43
Description		long intergenic non-protein coding RNA 1558	centrosomal protein 43
Image		No pdb structure
GO Annotations	Cellular Component		Nucleus Cytoplasm Centrosome Centriole Microtubule Organizing Center Cytosol Cytoskeleton Microtubule Cytoskeleton Cell Projection Perinuclear Region Of Cytoplasm
	Molecular Function		Protein Binding Protein Kinase Binding Protein Tyrosine Kinase Inhibitor Activity Protein Homodimerization Activity
	Biological Process		Negative Regulation Of Protein Kinase Activity Positive Regulation Of Cell Population Proliferation Cell Projection Organization Positive Regulation Of Cell Growth Positive Regulation Of Cell Migration Microtubule Anchoring
Pathways			Signaling by cytosolic FGFR1 fusion mutants Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane Signaling by FGFR1 in disease AURKA Activation by TPX2
Drugs
Diseases
GWAS		Heel bone mineral density ( 30598549)
Interacting Genes		1 interacting genes: PTPN11	4 interacting genes: NAGK OGT PPP2R1B S100A6
Entrez ID		26238	11116
HPRD ID		12846	10392
Ensembl ID		ENSG00000198221	ENSG00000213066
Uniprot IDs			A0A087WV25 B4DH64 O95684
PDB IDs			2D68
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cortisol Secretion Negative Regulation Of Growth Hormone Secretion Non-membrane Spanning Protein Tyrosine Phosphatase Activity Negative Regulation Of Neutrophil Activation Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Atrioventricular Canal Development Microvillus Organization Negative Regulation Of Glucocorticoid Secretion Regulation Of Neutrophil Activation Protein Kinase Binding Peptide Hormone Receptor Binding Negative Regulation Of Cell Adhesion Mediated By Integrin Bergmann Glial Cell Differentiation Intestinal Epithelial Cell Migration Neutrophil Activation Involved In Immune Response Cerebellar Cortex Formation Protein Tyrosine Kinase Inhibitor Activity Regulation Of Growth Hormone Secretion Neurotrophin TRK Receptor Signaling Pathway Insulin Receptor Binding Peptidyl-tyrosine Dephosphorylation Platelet Formation Positive Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of Chondrocyte Differentiation Positive Regulation Of Cellular Response To Insulin Stimulus Megakaryocyte Development Microtubule Anchoring Genitalia Development Regulation Of Type I Interferon-mediated Signaling Pathway Protein Tyrosine Kinase Binding Positive Regulation Of Interferon-beta Production Neurotrophin Signaling Pathway Negative Regulation Of Insulin Secretion Signaling Receptor Complex Adaptor Activity Astrocyte Differentiation Phosphotyrosine Residue Binding Cellular Response To Epidermal Growth Factor Stimulus Regulation Of Protein Export From Nucleus Positive Regulation Of D-glucose Import Positive Regulation Of D-glucose Transmembrane Transport Face Morphogenesis T Cell Costimulation Homeostasis Of Number Of Cells Within A Tissue Cell Projection Organization Negative Regulation Of Type I Interferon Production Platelet-derived Growth Factor Receptor Signaling Pathway Regulation Of Lipopolysaccharide-mediated Signaling Pathway Negative Regulation Of Peptide Secretion Negative Regulation Of Lipid Transport Epithelial Cell Migration	Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Ribonuclease T2 Activity N-acetylglucosamine Kinase Activity Muramyl Dipeptide Kinase Activity
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