INTS1 and DNAAF5

		INTS1	DNAAF5
Description		integrator complex subunit 1	dynein axonemal assembly factor 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Membrane Nuclear Membrane Integrator Complex INTAC Complex	Nucleolus Cytoplasm Cytosol Microtubule Cytoskeleton Motile Cilium Mitotic Spindle Dynein Axonemal Particle
	Molecular Function	Protein Binding	Dynein Intermediate Chain Binding
	Biological Process	Blastocyst Growth Inner Cell Mass Cell Proliferation Embryo Implantation SnRNA Processing Regulation Of Transcription Elongation By RNA Polymerase II U2 SnRNA 3'-end Processing Negative Regulation Of Apoptotic Process RNA Polymerase II Transcription Initiation Surveillance	Cilium Movement Cell Projection Organization Outer Dynein Arm Assembly Inner Dynein Arm Assembly
Pathways		RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes
Drugs
Diseases
GWAS		Executive inhibition (Stroop WIT and CIT) in attention deficit hyperactivity disorder ( 28416812)	Cerebrospinal P-tau181p levels ( 28247064) Initial pursuit acceleration ( 29064472) Retinitis pigmentosa ( 33514863)
Interacting Genes		4 interacting genes: CTDP1 DEAF1 MTNR1B RNF10	5 interacting genes: FEZ1 PFKL USP39 WEE2-AS1 ZBTB16
Entrez ID		26173	54919
HPRD ID		10899	07903
Ensembl ID		ENSG00000164880	ENSG00000164818
Uniprot IDs		Q8N201	B3KPE2 Q86Y56
PDB IDs		7CUN 7PKS 7YCX 8RBX 8RBZ 8RC4 8YJB
Enriched GO Terms of Interacting Partners?		Melatonin Receptor Activity Positive Regulation Of Transmission Of Nerve Impulse Positive Regulation Of Circadian Sleep/wake Cycle, Sleep Negative Regulation Of CGMP-mediated Signaling Regulation Of Nervous System Process Regulation Of Neuronal Action Potential Negative Regulation Of Transmission Of Nerve Impulse Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Regulation Of System Process Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep TFIIF-class Transcription Factor Complex Binding RNA Polymerase II CTD Heptapeptide Repeat Phosphatase Activity Postsynapse To Nucleus Signaling Pathway Extrinsic Component Of Postsynaptic Density Membrane Negative Regulation Of Schwann Cell Proliferation
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