SUSD5 and DYNC1LI1

		SUSD5	DYNC1LI1
Description		sushi domain containing 5	dynein cytoplasmic 1 light intermediate chain 1
Image		No pdb structure
GO Annotations	Cellular Component	Membrane	Chromosome, Centromeric Region Kinetochore Spindle Pole Chromosome Cytoplasm Endosome Centrosome Cytosol Cytoskeleton Cytoplasmic Dynein Complex Microtubule Plasma Membrane Membrane Dynein Complex Endocytic Vesicle Membrane Secretory Granule Membrane Recycling Endosome Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Hyaluronic Acid Binding	Nucleotide Binding RNA Binding Protein Binding ATP Binding GTP Binding GDP Binding Protein-macromolecule Adaptor Activity Dynein Heavy Chain Binding Molecular Adaptor Activity
	Biological Process	Cell Adhesion Notch Signaling Pathway	Microtubule Cytoskeleton Organization Microtubule-based Movement Cell Division Regulation Of Vesicle-mediated Transport Early Endosome To Recycling Endosome Transport Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint
Pathways			Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand RHO GTPases Activate Formins Neutrophil degranulation COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Anorectal malformation ( 31136621) Appendicular lean mass ( 33097823) Arterial stiffness index ( 31235810) Asthma ( 31619474 31959851) Heel bone mineral density ( 28869591) Hip circumference adjusted for BMI ( 34021172) Refractive error ( 32231278)	Bitter taste perception (6-n-propylthiouracil) in obesity with metabolic syndrome ( 31005965) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Low density lipoprotein cholesterol levels ( 33339817)
Interacting Genes			11 interacting genes: BRCA2 CEBPA IKBKG NOP56 NUP85 OGT PGAM2 RAB4A REL RUFY1 SLC25A21-AS1
Entrez ID		26032	51143
HPRD ID		19399	10917
Ensembl ID		ENSG00000173705	ENSG00000144635
Uniprot IDs		O60279	B3KM42 E9PHI6 Q9Y6G9
PDB IDs			6B9H 6PSD 6PSE
Enriched GO Terms of Interacting Partners?		Cytoplasmic Dynein Complex Dynein Heavy Chain Binding Positive Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Regulation Of Mitotic Cell Cycle Spindle Assembly Checkpoint Early Endosome To Recycling Endosome Transport Positive Regulation Of Cell Cycle Checkpoint Dynein Complex Ficolin-1-rich Granule Membrane Regulation Of Mitotic Sister Chromatid Separation Endocytic Vesicle Membrane GDP Binding Regulation Of Chromosome Separation Regulation Of Mitotic Metaphase/anaphase Transition Secretory Granule Membrane Recycling Endosome Membrane Regulation Of Sister Chromatid Segregation Regulation Of Mitotic Nuclear Division Regulation Of Chromosome Segregation Regulation Of Nuclear Division Chromosome, Centromeric Region Spindle Pole Kinetochore Molecular Adaptor Activity Protein-macromolecule Adaptor Activity Regulation Of Chromosome Organization Positive Regulation Of Cell Cycle Process Endosomal Transport Microtubule Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle
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