CLIP3 and CEP83

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CLIP3	CEP83
Description		CAP-Gly domain containing linker protein 3	centrosomal protein 83
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Golgi Apparatus Golgi Stack Trans-Golgi Network Cytosol Plasma Membrane Cell Cortex Membrane Early Endosome Membrane Trans-Golgi Network Membrane Microtubule Plus-end Membrane Raft Recycling Endosome Membrane	Cytoplasm Golgi Apparatus Centrosome Centriole Cytosol Cytoskeleton Ciliary Transition Fiber
	Molecular Function	Protein Binding Microtubule Binding Ganglioside Binding Microtubule Plus-end Binding	Protein Binding Identical Protein Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Positive Regulation Of D-glucose Transmembrane Transport Peptidyl-L-cysteine S-palmitoylation Negative Regulation Of Microtubule Polymerization Cytoplasmic Microtubule Organization Positive Regulation Of Apoptotic Process Membrane Biogenesis Fat Cell Differentiation Positive Regulation Of Endocytosis Protein Transport Along Microtubule Positive Regulation Of Protein Localization To Plasma Membrane	Cell Projection Organization Vesicle Docking Establishment Of Centrosome Localization Cilium Assembly Protein Localization To Centrosome
Pathways		Regulation of TNFR1 signaling	Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS			Asthma ( 31959851) Chloride levels ( 29403010) Femur bone mineral density x serum urate levels interaction ( 34046847) Sodium levels ( 29403010)
Interacting Genes		8 interacting genes: AKT1 AKT2 CEP83 FBXO7 GOLGA2 TLE5 TNFRSF1A TNFRSF21	8 interacting genes: ATF4 CBFA2T2 CLIP3 EHHADH LZTS1 RUNX1T1 UBC YES1
Entrez ID		25999	51134
HPRD ID		09572	14869
Ensembl ID		ENSG00000105270	ENSG00000173588
Uniprot IDs		Q96DZ5	F8VYN8 Q3B787 Q9Y592
PDB IDs		2CP0
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane Negative Regulation Of Fatty Acid Transport Regulation Of Long-chain Fatty Acid Import Into Cell Peripheral Nervous System Myelin Maintenance Negative Regulation Of PERK-mediated Unfolded Protein Response Mammary Gland Epithelial Cell Differentiation Glycogen Biosynthetic Process Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of PERK-mediated Unfolded Protein Response Regulation Of Fatty Acid Beta-oxidation Myelin Maintenance Positive Regulation Of Lipid Metabolic Process Positive Regulation Of Glycogen Biosynthetic Process Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Endoplasmic Reticulum Unfolded Protein Response Polysaccharide Biosynthetic Process Protein Localization To Plasma Membrane Regulation Of Glycogen Biosynthetic Process Regulation Of Fatty Acid Transport Regulation Of Fatty Acid Oxidation Lymphocyte Apoptotic Process Protein Localization To Cell Periphery Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of D-glucose Import Negative Regulation Of Lipid Transport Regulation Of Glycogen Metabolic Process Regulation Of Apoptotic Process Positive Regulation Of D-glucose Transmembrane Transport Regulation Of Myelination Regulation Of Programmed Cell Death Positive Regulation Of Glucose Metabolic Process Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Translational Initiation Leukocyte Apoptotic Process Negative Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of D-glucose Import Protein Localization To Membrane Regulation Of Lipid Catabolic Process Glycogen Metabolic Process Regulation Of Lipid Metabolic Process Positive Regulation Of Blood Vessel Endothelial Cell Migration Establishment Of Protein Localization To Mitochondrion Apoptotic Process Energy Reserve Metabolic Process Polysaccharide Metabolic Process Programmed Cell Death Intracellular Protein Localization Regulation Of TRNA Methylation Cellular Response To High Light Intensity
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