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SPDYA and DCAF7
SPDYA
DCAF7
Description
speedy/RINGO cell cycle regulator family member A
DDB1 and CUL4 associated factor 7
Image
No pdb structure
GO Annotations
Cellular Component
Chromosome, Telomeric Region
XY Body
Nucleus
Nuclear Envelope
Nucleoplasm
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Nuclear Matrix
Nuclear Body
Protein-containing Complex
Cul4-RING E3 Ubiquitin Ligase Complex
Molecular Function
Protein Binding
Protein Kinase Binding
Protein Kinase Activator Activity
Protein Binding
Protein-macromolecule Adaptor Activity
Biological Process
G1/S Transition Of Mitotic Cell Cycle
DNA Damage Response
Male Meiotic Nuclear Division
Spermatogenesis
Positive Regulation Of Cell Population Proliferation
Telomere Capping
Positive Regulation Of Protein Kinase Activity
Oogenesis
Meiotic Attachment Of Telomere To Nuclear Envelope
Establishment Of Protein Localization To Telomere
Protein Ubiquitination
Pathways
Association of TriC/CCT with target proteins during biosynthesis
Neddylation
Drugs
Diseases
GWAS
Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) (
30940143
)
Hip circumference adjusted for BMI (
34021172
)
Interacting Genes
5 interacting genes:
AQP1
CDK2
CDK5
CDKN1B
FBXO7
7 interacting genes:
APP
ATP13A2
BMPR1B
DYRK1B
LIG1
PWP2
YWHAG
Entrez ID
245711
10238
HPRD ID
18095
09340
Ensembl ID
ENSG00000163806
ENSG00000136485
Uniprot IDs
A0A384MTT5
Q5MJ70
P61962
PDB IDs
5UQ1
5UQ2
5UQ3
7E34
Enriched GO Terms of Interacting Partners
?
Cellular Response To Nitric Oxide
Cellular Response To Reactive Nitrogen Species
Response To Nitric Oxide
Potassium Ion Transport
Negative Regulation Of Cell Cycle
Regulation Of Cell Cycle Phase Transition
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Metal Ion Transport
Regulation Of Cell Cycle G1/S Phase Transition
Cyclin-dependent Protein Serine/threonine Kinase Activity
Negative Regulation Of Mitotic Cell Cycle
Cyclin Binding
Monoatomic Cation Transport
Sensory Perception Of Pain
Regulation Of Cell Cycle Process
Positive Regulation Of DNA Replication
Cyclin-dependent Protein Kinase Holoenzyme Complex
Metanephric Descending Thin Limb Development
Metanephric Proximal Straight Tubule Development
Nitric Oxide Transmembrane Transporter Activity
Metanephric Proximal Convoluted Tubule Segment 2 Development
Monoatomic Ion Transport
Negative Regulation Of Cell Cycle G1/S Phase Transition
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Mitotic Cell Cycle Phase Transition
Cellular Senescence
Negative Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter
Positive Regulation Of Presynaptic Cytosolic Calcium Concentration
Cyclin-dependent Protein Kinase Regulator Activity
Glial Cytoplasmic Inclusion
Classical Lewy Body
Lewy Body Corona
Lewy Neurite
Regulation Of Cell Cycle
Regulation Of Locomotion
G1/S Transition Of Mitotic Cell Cycle
Cell Cycle G1/S Phase Transition
Sensory Perception
Metanephric Glomerulus Vasculature Development
Glycerol Transmembrane Transporter Activity
Corticotropin Secretion
Regulation Of Mitotic Cell Cycle
Y Chromosome
Positive Regulation Of Heterochromatin Formation
Cyclin A1-CDK2 Complex
Cyclin E2-CDK2 Complex
Positive Regulation Of DNA-templated DNA Replication Initiation
Acetylcholine Receptor Activator Activity
Negative Regulation Of Developmental Growth
Negative Regulation Of Cardiac Muscle Tissue Regeneration
Cellular Response To Manganese Ion
Response To Manganese Ion
Cellular Response To Stress
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Tagcloud (Intersection)
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