CLDN15 and SLC35B2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CLDN15	SLC35B2
Description		claudin 15	solute carrier family 35 member B2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Bicellular Tight Junction Membrane Lateral Plasma Membrane Tight Junction Anchoring Junction	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Membrane
	Molecular Function	Structural Molecule Activity Identical Protein Binding Paracellular Tight Junction Channel Activity	Protein Binding Antiporter Activity 3'-phosphoadenosine 5'-phosphosulfate Transmembrane Transporter Activity
	Biological Process	Monoatomic Ion Transport Cell Adhesion Calcium-independent Cell-cell Adhesion Via Plasma Membrane Cell-adhesion Molecules Bicellular Tight Junction Assembly Paracellular Transport Regulation Of Intestinal D-glucose Absorption Regulation Of Intestinal Lipid Absorption	Positive Regulation Of Canonical NF-kappaB Signal Transduction 3'-phosphoadenosine 5'-phosphosulfate Transport Chondroitin Sulfate Proteoglycan Biosynthetic Process Transmembrane Transport 5'-adenylyl Sulfate Transmembrane Transport 3'-phospho-5'-adenylyl Sulfate Transmembrane Transport
Pathways		Tight junction interactions	Transport and metabolism of PAPS Transport of nucleotide sugars
Drugs
Diseases
GWAS			Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		3 interacting genes: GEM PLPP6 SLC35B2	12 interacting genes: AQP6 ASGR2 CD69 CLDN15 CREB3L1 CYB5R3 ERGIC3 LMNA SHISAL1 TEX29 TMEM237 TMEM248
Entrez ID		24146	347734
HPRD ID		13065	11576
Ensembl ID		ENSG00000106404	ENSG00000157593
Uniprot IDs		P56746	Q8TB61
PDB IDs
Enriched GO Terms of Interacting Partners?		3'-phosphoadenosine 5'-phosphosulfate Transport 5'-adenylyl Sulfate Transmembrane Transport 3'-phospho-5'-adenylyl Sulfate Transmembrane Transport 3'-phosphoadenosine 5'-phosphosulfate Transmembrane Transporter Activity Isoprenoid Diphosphate Phosphatase Activity Farnesyl Diphosphate Catabolic Process Geranylgeranyl Diphosphate Catabolic Process Geranyl Diphosphate Metabolic Process Positive Regulation Of Neutrophil Activation Lipid Phosphatase Activity Farnesyl Diphosphate Metabolic Process Sphingosine-1-phosphate Phosphatase Activity Lysophosphatidic Acid Phosphatase Activity Protein Prenylation Regulation Of Neutrophil Activation Phosphatidate Phosphatase Activity Chondroitin Sulfate Proteoglycan Biosynthetic Process Nucleotide Transmembrane Transport Spindle Midzone Chondroitin Sulfate Proteoglycan Metabolic Process Purine-containing Compound Transmembrane Transport Purine Nucleotide Transport Nucleotide Transport Adenine Nucleotide Transport Phospholipid Dephosphorylation Cholesterol Biosynthetic Process Phospholipid Catabolic Process Sterol Biosynthetic Process Calcium Channel Regulator Activity Nuclear Inner Membrane Metaphase Chromosome Alignment Endoplasmic Reticulum Membrane Proteoglycan Biosynthetic Process GDP Binding Carbohydrate Derivative Transport
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