NUP210 and ADGRG2

		NUP210	ADGRG2
Description		nucleoporin 210	adhesion G protein-coupled receptor G2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Pore Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Nuclear Membrane	Cytosol Plasma Membrane Cell Surface Membrane Apical Plasma Membrane Extracellular Exosome
	Molecular Function	Protein Binding	Transmembrane Signaling Receptor Activity G Protein-coupled Receptor Activity Protein Binding
	Biological Process	Nucleocytoplasmic Transport Protein Transport MRNA Transport	Signal Transduction Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Spermatogenesis Spermatid Development
Pathways		ISG15 antiviral mechanism Transport of the SLBP independent Mature mRNA Transport of the SLBP Dependant Mature mRNA Transport of Mature mRNA Derived from an Intronless Transcript Transport of Mature mRNA derived from an Intron-Containing Transcript Rev-mediated nuclear export of HIV RNA Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Viral Messenger RNA Synthesis NEP/NS2 Interacts with the Cellular Export Machinery Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear import of Rev protein Vpr-mediated nuclear import of PICs IPs transport between nucleus and cytosol IP3 and IP4 transport between cytosol and nucleus IP6 and IP7 transport between cytosol and nucleus snRNP Assembly SUMOylation of DNA damage response and repair proteins SUMOylation of ubiquitinylation proteins Nuclear Pore Complex (NPC) Disassembly Regulation of HSF1-mediated heat shock response SUMOylation of SUMOylation proteins SUMOylation of chromatin organization proteins SUMOylation of RNA binding proteins SUMOylation of DNA replication proteins SUMOylation of DNA replication proteins Transcriptional regulation by small RNAs Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) tRNA processing in the nucleus HCMV Early Events HCMV Late Events SARS-CoV-2 activates/modulates innate and adaptive immune responses
Drugs
Diseases
GWAS		Coronary artery disease in type 1 diabetes ( 29695241)
Interacting Genes		4 interacting genes: CDK1 EXOSC5 MTDH TRIP6
Entrez ID		23225	10149
HPRD ID		06368	04040
Ensembl ID		ENSG00000132182	ENSG00000173698
Uniprot IDs		Q8TEM1	A8K4P7 Q499H0 Q8IZP9
PDB IDs		7R5J 7R5K
Enriched GO Terms of Interacting Partners?			Nuclear Transport Nucleocytoplasmic Transport Nucleobase-containing Compound Transport RNA Transport Nuclear Membrane Nuclear Envelope MRNA Transport Nuclear Pore
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