LARP4B and TUBB8

		LARP4B	TUBB8
Description		La ribonucleoprotein 4B	tubulin beta 8 class VIII
Image			No pdb structure
GO Annotations	Cellular Component	Nucleolus Cytoplasm Cytosol Cytoplasmic Stress Granule Membrane	Cytoplasm Spindle Cytoskeleton Microtubule Microtubule Cytoskeleton Intercellular Bridge Extracellular Exosome Mitotic Spindle Meiotic Spindle
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA 3'-UTR Binding Protein Binding	Nucleotide Binding GTPase Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding Metal Ion Binding
	Biological Process	Regulation Of Translation Positive Regulation Of Translation Positive Regulation Of 3'-UTR-mediated MRNA Stabilization	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Oocyte Maturation Microtubule-based Process Spindle Assembly Involved In Female Meiosis
Pathways			Translocation of SLC2A4 (GLUT4) to the plasma membrane Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Gap junction assembly MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Recruitment of NuMA to mitotic centrosomes Recycling pathway of L1 Recycling pathway of L1 Cargo trafficking to the periciliary membrane RHO GTPases activate IQGAPs RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase The role of GTSE1 in G2/M progression after G2 checkpoint Carboxyterminal post-translational modifications of tubulin Carboxyterminal post-translational modifications of tubulin HCMV Early Events Assembly and cell surface presentation of NMDA receptors Activation of AMPK downstream of NMDARs Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation Sealing of the nuclear envelope (NE) by ESCRT-III Kinesins PKR-mediated signaling
Drugs
Diseases
GWAS		Basophil count ( 32888494) Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 27863252 32888494) Bisphosphonate-associated atypical femoral fracture ( 31006051) Blood urea nitrogen levels ( 31152163) Chronic kidney disease ( 31152163) Chronotype ( 30696823) Estimated glomerular filtration rate ( 31015462 31451708 31152163) Estimated glomerular filtration rate in non-diabetics ( 31451708) Femur bone mineral density x serum urate levels interaction ( 34046847) Neutrophil percentage of granulocytes ( 27863252) Prostate cancer ( 29892016) Prostate cancer (advanced) ( 29892016) Prostate cancer (early onset) ( 29892016) Reticulocyte fraction of red cells ( 32888494) Sum eosinophil basophil counts ( 27863252) White blood cell count (basophil) ( 27863252)
Interacting Genes		7 interacting genes: ATXN1L C1QTNF9 DMRTB1 MAGED1 OGT PABPC1 RBPMS	1 interacting genes: UBASH3A
Entrez ID		23185	347688
HPRD ID		13787	18244
Ensembl ID		ENSG00000107929	ENSG00000261456
Uniprot IDs		Q92615	Q3ZCM7
PDB IDs		3PTH
Enriched GO Terms of Interacting Partners?		Dimethylallyl Diphosphate Biosynthetic Process Isopentenyl-diphosphate Delta-isomerase Activity Intramolecular Oxidoreductase Activity Isopentenyl Diphosphate Biosynthetic Process Isopentenyl Diphosphate Metabolic Process Isoprenoid Biosynthetic Process Cholesterol Biosynthetic Process Sterol Biosynthetic Process Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly	Positive Regulation Of 3'-UTR-mediated MRNA Stabilization
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