FOXK1 and IRF2

Number of citations of the paper that reports this interaction (PMID 21903422)
33

Data Source:
BioGRID (affinity chromatography technology, pull down)

		FOXK1	IRF2
Gene Name		forkhead box K1	interferon regulatory factor 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Nucleoplasm Cytoplasm Cytosol Focal Adhesion
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Protein Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Muscle Organ Development Cell Differentiation Negative Regulation Of Cell Growth Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Regulation Of Transcription, DNA-templated Blood Coagulation Cell Proliferation Cytokine-mediated Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Interferon-gamma-mediated Signaling Pathway Type I Interferon Signaling Pathway
Pathways			Interferon gamma signaling RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways Interferon Signaling TRAF6 mediated IRF7 activation Cytokine Signaling in Immune system Interferon alpha/beta signaling Factors involved in megakaryocyte development and platelet production Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: IRF2	22 interactors: APP ATG7 BRD7 CSNK2A1 EP300 FKBP7 FOXK1 FOXK2 HMGB1 HMGN1 IRF1 IRF2BP1 IRF2BP2 IRF8 KAT2A KAT2B MDM2 NFKB1 PPP3CB PRKACA RELA STAT1
Entrez ID		221937	3660
HPRD ID		18750	00962
Ensembl ID		ENSG00000164916	ENSG00000168310
Uniprot IDs		P85037	P14316
PDB IDs
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Innate Immune Response Regulation Of Gene Expression RNA Biosynthetic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Transcription, DNA-templated Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Cellular Nitrogen Compound Metabolic Process Immune Response Negative Regulation Of Biosynthetic Process Defense Response Cellular Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Response To Abiotic Stimulus Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Negative Regulation Of Gene Expression Regulation Of Interleukin-12 Biosynthetic Process Regulation Of Protein Metabolic Process Apoptotic Process Programmed Cell Death Response To External Stimulus Biosynthetic Process Cell Death Death Regulation Of Interleukin-12 Production Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Viral Process
Tagcloud ?		1b adenovirus cooperative ctbp ctbp1 ctbp2 dissect dyrk1a e1a engineered han11 immortalization immunocompetent immunodeficient influencing k2 p400 pldls prb productive ras replication restrict retinoblastoma rodent suppresses transformation trrap tumorigenic	artp calculating chief convergence dusp2 hrgg il2ra il6 il8ra il8rb infgr1 map3k10 merits mmp1 nfkb1a nos2a partp pik3ca polygenic pttrnd raf1 rectal runx3 sepx1 smad3 soc strongest truncation tyk2
Tagcloud (Difference) ?		1b adenovirus cooperative ctbp ctbp1 ctbp2 dissect dyrk1a e1a engineered han11 immortalization immunocompetent immunodeficient influencing k2 p400 pldls prb productive ras replication restrict retinoblastoma rodent suppresses transformation trrap tumorigenic	artp calculating chief convergence dusp2 hrgg il2ra il6 il8ra il8rb infgr1 map3k10 merits mmp1 nfkb1a nos2a partp pik3ca polygenic pttrnd raf1 rectal runx3 sepx1 smad3 soc strongest truncation tyk2
Tagcloud (Intersection) ?