C8orf74 and PRSS55

		C8orf74	PRSS55
Description		chromosome 8 open reading frame 74	serine protease 55
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Acrosomal Vesicle Cytoplasm Cytosol Plasma Membrane Membrane Side Of Membrane
	Molecular Function	Protein Binding	Serine-type Endopeptidase Activity Peptidase Activity Serine-type Peptidase Activity Hydrolase Activity
	Biological Process		Proteolysis Binding Of Sperm To Zona Pellucida Flagellated Sperm Motility
Pathways
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301) Autism spectrum disorder ( 30804558) Brain morphology (MOSTest) ( 32665545) Cooked vegetable consumption ( 32066663) Fish- and plant-related diet ( 32066663) Processed meat consumption ( 32066663) Suicide ( 26079190)	A body shape index ( 34021172) Barrett's esophagus or Esophageal adenocarcinoma ( 32918910) Barrett's esophagus or esophageal adenocarcinoma x sex interaction (2df test) ( 32918910) Brain morphology (MOSTest) ( 32665545) General factor of neuroticism ( 30867560) Obesity-related traits ( 23251661) Refractive error ( 32231278) Smoking status (ever vs never smokers) ( 30643258) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		8 interacting genes: KDM1A PRMT6 SUV39H1 SUV39H2 TRIM54 TRIM55 TRIM63 ZNF655
Entrez ID		203076	203074
HPRD ID		19096	07162
Ensembl ID		ENSG00000171060	ENSG00000184647
Uniprot IDs		A0AAG2TK55 Q6P047	Q6UWB4
PDB IDs
Enriched GO Terms of Interacting Partners?		Histone H3 Methyltransferase Activity Defense Response To Other Organism Defense Response To Symbiont Histone Methyltransferase Activity Histone H3K9 Trimethyltransferase Activity Innate Immune Response Response To Other Organism Immune Response Response To Stress Histone H3K9 Methyltransferase Activity Response To External Biotic Stimulus Defense Response Epigenetic Programming In The Zygotic Pronuclei Defense Response To Bacterium Response To Bacterium Methyltransferase Activity Immune System Process Epigenetic Programming Of Gene Expression Methylation Histone H2AR3 Methyltransferase Activity Epigenetic Regulation Of Gene Expression Chromatin Remodeling Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Histone H3R2 Methyltransferase Activity Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation ENoSc Complex Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Histone Arginine N-methyltransferase Activity Microtubule Defense Response To Gram-negative Bacterium Zinc Ion Binding Ubiquitin Protein Ligase Activity Protein Demethylase Activity CCR2 Chemokine Receptor Binding RDNA Heterochromatin Chromatin Organization MRF Binding Protein-arginine Omega-N Monomethyltransferase Activity Histone H4R3 Methyltransferase Activity Skeletal Muscle Atrophy Defense Response To Gram-positive Bacterium Regulation Of Signal Transduction By P53 Class Mediator
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