ANO6 and REDIC1

		ANO6	REDIC1
Description		anoctamin 6	regulator of DNA class I crossover intermediates 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Cell Surface Membrane Monoatomic Ion Channel Complex Chloride Channel Complex Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane	Chromosome
	Molecular Function	Calcium-activated Cation Channel Activity Intracellularly Calcium-gated Chloride Channel Activity Voltage-gated Monoatomic Ion Channel Activity Voltage-gated Chloride Channel Activity Chloride Channel Activity Protein Binding Phospholipid Scramblase Activity Metal Ion Binding Protein Dimerization Activity	DNA Binding RNA Binding Protein Binding
	Biological Process	Activation Of Blood Coagulation Via Clotting Cascade Monoatomic Ion Transport Chloride Transport Lipid Transport Blood Coagulation Plasma Membrane Phospholipid Scrambling Positive Regulation Of Bone Mineralization Bleb Assembly Monoatomic Ion Transmembrane Transport Positive Regulation Of Monoatomic Ion Transmembrane Transport Purinergic Nucleotide Receptor Signaling Pathway Sodium Ion Transmembrane Transport Positive Regulation Of Apoptotic Process Negative Regulation Of Cell Volume Pore Complex Assembly Positive Regulation Of Phagocytosis, Engulfment Calcium Activated Phosphatidylserine Scrambling Calcium Activated Phosphatidylcholine Scrambling Calcium Ion Transmembrane Transport Positive Regulation Of Monocyte Chemotaxis Phosphatidylserine Exposure On Blood Platelet Chloride Transmembrane Transport Positive Regulation Of Potassium Ion Export Across Plasma Membrane Positive Regulation Of Endothelial Cell Apoptotic Process	Meiotic Cell Cycle
Pathways		Stimuli-sensing channels Neutrophil degranulation Induction of Cell-Cell Fusion
Drugs
Diseases
GWAS		Ankylosing spondylitis ( 22138694) Insomnia ( 29520036) Urate levels in obese individuals ( 25811787) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes			5 interacting genes: DYNLL1 DYNLL2 LMO4 NXF1 TNPO2
Entrez ID		196527	283461
HPRD ID		18746	08806
Ensembl ID		ENSG00000177119	ENSG00000180116
Uniprot IDs		A0A7P0TBC5 B3KX12 Q4KMQ2	Q86WS4
PDB IDs
Enriched GO Terms of Interacting Partners?		Myo-inositol Transmembrane Transporter Activity Myo-inositol:proton Symporter Activity Cellular Response To Curcumin Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Caveola Neck Negative Regulation Of Late Endosome To Lysosome Transport Amphisome Peroxidase Inhibitor Activity Negative Regulation Of Protein Processing Involved In Protein Targeting To Mitochondrion GTP-dependent Protein Kinase Activity Beta-catenin Destruction Complex Binding Wnt Signalosome Assembly Anterior Visceral Endoderm Cell Migration Negative Regulation Of Cardiac Muscle Cell Myoblast Differentiation Regulation Of Myoblast Differentiation Establishment Of Bipolar Cell Polarity Involved In Cell Morphogenesis Polarized Secretion Of Basement Membrane Proteins In Epithelium Focal Adhesion Disassembly Cell Trailing Edge Dolichyl Pyrophosphate Glc2Man9GlcNAc2 Alpha-1,2-glucosyltransferase Activity UDP-D-xylose:beta-D-glucoside Alpha-1,3-D-xylosyltransferase Activity Myo-inositol Transport Positive Regulation Of Protein Autoubiquitination Response To Curcumin Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Ubiquitination Positive Regulation Of Proteasomal Protein Catabolic Process Extracellular Matrix Constituent Secretion Tear Secretion Protein Import Into Nucleus Synaptic Vesicle Growth Cone Cytoplasmic Side Of Mitochondrial Outer Membrane Positive Regulation Of Post-translational Protein Modification Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Import Into Nucleus Positive Regulation Of Dopamine Receptor Signaling Pathway Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Multivesicular Body, Internal Vesicle Regulation Of Postsynapse Organization Regulation Of CAMKK-AMPK Signaling Cascade Regulation Of Branching Morphogenesis Of A Nerve Regulation Of Synaptic Vesicle Transport Embryonic Nail Plate Morphogenesis Maintenance Of Postsynaptic Density Structure UDP-xylosyltransferase Activity Regulation Of Protein Autoubiquitination Positive Regulation Of Synaptic Vesicle Endocytosis Negative Regulation Of Protein Targeting To Mitochondrion Regulation Of Kidney Size	Cytoplasmic Dynein Complex Dynein Intermediate Chain Binding Dynein Complex Microtubule Associated Complex Ciliary Tip Tertiary Granule Membrane Scaffold Protein Binding Myosin V Complex Phosphatidylserine Exposure On Blood Platelet Negative Regulation Of DNA Strand Resection Involved In Replication Fork Processing Activation Of Blood Coagulation Via Clotting Cascade Ventral Spinal Cord Interneuron Differentiation Deoxyribonuclease Inhibitor Activity Regulation Of DNA Strand Resection Involved In Replication Fork Processing Nitric-oxide Synthase Inhibitor Activity Calcium Activated Phosphatidylserine Scrambling Positive Regulation Of Potassium Ion Export Across Plasma Membrane Calcium Activated Phospholipid Scrambling Calcium Activated Phosphatidylcholine Scrambling Negative Regulation Of Cell Volume Spinal Cord Motor Neuron Cell Fate Specification Plasma Membrane Bounded Cell Projection Organization Nuclear RNA Export Factor Complex Spinal Cord Association Neuron Differentiation Cell Projection Organization Nitric-oxide Synthase Regulator Activity Intraciliary Retrograde Transport Microtubule Cytoskeleton Negative Regulation Of DNA-templated DNA Replication Nuclear Transport Nucleocytoplasmic Transport Nuclear Inclusion Body Transcription Export Complex 9+0 Non-motile Cilium Calcium-activated Cation Channel Activity Regulation Of Potassium Ion Export Across Plasma Membrane Voltage-gated Monoatomic Ion Channel Activity Voltage-gated Chloride Channel Activity Positive Regulation Of Phagocytosis, Engulfment Bleb Assembly DNA Strand Resection Involved In Replication Fork Processing Negative Regulation Of Nitric Oxide Biosynthetic Process Microtubule Intracellular Transport Intracellularly Calcium-gated Chloride Channel Activity Protein-containing Complex Binding Plasma Membrane Bounded Cell Projection Assembly
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