IDO2 and HOOK3

		IDO2	HOOK3
Description		indoleamine 2,3-dioxygenase 2	hook microtubule tethering protein 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Pericentriolar Material Cytoplasm Golgi Apparatus Cis-Golgi Network Centrosome Cytoskeleton Microtubule HOPS Complex Centriolar Satellite FHF Complex
	Molecular Function	Tryptophan 2,3-dioxygenase Activity Protein Binding Oxidoreductase Activity Heme Binding Indoleamine 2,3-dioxygenase Activity Metal Ion Binding Dioxygenase Activity	Protein Binding Microtubule Binding Dynactin Binding Identical Protein Binding Dynein Light Chain Binding Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding
	Biological Process	Immune System Process L-tryptophan Catabolic Process L-tryptophan Catabolic Process To Kynurenine 'de Novo' NAD+ Biosynthetic Process From L-tryptophan	Endosome Organization Lysosome Organization Endosome To Lysosome Transport Protein Transport Interkinetic Nuclear Migration Cytoskeleton-dependent Intracellular Transport Cytoplasmic Microtubule Organization Microtubule Anchoring At Centrosome Early Endosome To Late Endosome Transport Negative Regulation Of Neurogenesis Golgi Localization Protein Localization To Centrosome Neuronal Stem Cell Population Maintenance Protein Localization To Perinuclear Region Of Cytoplasm
Pathways		Tryptophan catabolism
Drugs
Diseases
GWAS		Schizophrenia x sex interaction ( 34099189)	Zinc levels ( 26025379)
Interacting Genes		2 interacting genes: BANP LZTS1	11 interacting genes: AKTIP CTIF EIF4ENIF1 HOOK1 HOOK2 KRT13 MAPT MEOX2 PNMA5 VPS16 VPS41
Entrez ID		169355	84376
HPRD ID		14113	09699
Ensembl ID		ENSG00000188676	ENSG00000168172
Uniprot IDs		Q6ZQW0	Q86VS8
PDB IDs			5J8E 6B9H 8QAT 9KNS 9KO8
Enriched GO Terms of Interacting Partners?			HOPS Complex Endosome To Lysosome Transport FHF Complex Lysosomal Transport Protein Localization To Perinuclear Region Of Cytoplasm Vacuolar Transport Early Endosome To Late Endosome Transport Vesicle Organization Vacuole Organization Intracellular Transport Cytoplasmic Microtubule Organization Lysosome Organization Microtubule Binding Endosome Organization Endosomal Transport Cellular Localization Establishment Of Localization In Cell Regulation Of SNARE Complex Assembly Endosomal Vesicle Fusion Protein Transport Organelle Organization Establishment Of Protein Localization Dynein Light Intermediate Chain Binding Supramolecular Fiber Organization Cytoskeleton-dependent Intracellular Transport Histone-dependent DNA Binding Tubulin Complex Microtubule Lateral Binding Negative Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Microtubule Cytoskeleton Intracellular Protein Localization Vesicle-mediated Transport Neurofibrillary Tangle Assembly Clathrin-coated Vesicle Lysosomal HOPS Complex Regulation Of Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Vacuole Fusion, Non-autophagic Indoleamine 2,3-dioxygenase Activity Cytoplasmic Ribonucleoprotein Granule Microtubule Tryptophan 2,3-dioxygenase Activity Vesicle Fusion Actin Binding Organelle Membrane Fusion PML Body Vesicle Tethering Complex Regulation Of Translation Regulation Of Protein Metabolic Process Main Axon Negative Regulation Of Mitochondrial Fission
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