LIX1 and TSACC

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LIX1	TSACC
Description		limb and CNS expressed 1	TSSK6 activating cochaperone
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Cytoplasm
	Molecular Function	Protein Binding	Protein Binding Protein-folding Chaperone Binding
	Biological Process	Autophagosome Maturation
Pathways
Drugs
Diseases
GWAS			Age at first sexual intercourse ( 34211149)
Interacting Genes		5 interacting genes: APPL2 DOK4 EMSY FAM110A TSACC	4 interacting genes: DTNB FOXP2 KDM1A LIX1
Entrez ID		167410	128229
HPRD ID		08069	10252
Ensembl ID		ENSG00000145721	ENSG00000163467
Uniprot IDs		Q8N485	Q96A04 V9GYT6
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Macropinocytosis Positive Regulation Of Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Early Phagosome Membrane Cold Acclimation	Cerebral Cortex Development Putamen Development Caudate Nucleus Development Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Response To Fungicide MRF Binding Histone H3K4 Demethylase Activity Guanine Metabolic Process Protein Demethylase Activity Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Righting Reflex Vocal Learning Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Observational Learning Epithelial Cell Proliferation Involved In Lung Morphogenesis Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Neuron Differentiation Histone H3K9 Demethylase Activity Positive Regulation Of Cell Size Cerebellar Purkinje Cell Differentiation Inhibitory Synapse DNA Repair Complex Auditory Behavior Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Mechanosensory Behavior Purine Nucleobase Metabolic Process Histone Demethylase Activity Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Reflex Cell Differentiation In Hindbrain Vocalization Behavior Smooth Muscle Tissue Development Nuclear Androgen Receptor Binding Positive Regulation Of Neuroblast Proliferation Telomeric DNA Binding Histone Methyltransferase Complex Regulation Of Chromatin Organization Cellular Response To Gamma Radiation DNA Repair-dependent Chromatin Remodeling Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Positive Regulation Of Mesenchymal Cell Proliferation Neuron Maturation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Response To Antibiotic Regulation Of Androgen Receptor Signaling Pathway Regulation Of Mesenchymal Cell Proliferation
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