EXD1 and EML2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		EXD1	EML2
Description		exonuclease 3'-5' domain containing 1	EMAP like 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm P Granule PET Complex	Cytoplasm Spindle Cytoskeleton Microtubule Microtubule Associated Complex Mitotic Spindle
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding 3'-5' Exonuclease Activity Protein Homodimerization Activity	Protein Binding Microtubule Binding Tubulin Binding
	Biological Process	Nucleobase-containing Compound Metabolic Process Regulatory NcRNA-mediated Gene Silencing PiRNA Processing Meiotic Cell Cycle	Microtubule Cytoskeleton Organization Visual Perception Sensory Perception Of Sound Regulation Of Microtubule Nucleation Negative Regulation Of Microtubule Polymerization
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Frailty index ( 34431594) Hematocrit ( 32888494) Systolic blood pressure ( 30578418) Ulcerative colitis ( 28067908)	Fruit consumption ( 32066663) Hemoglobin A1c levels ( 29403010) Subcutaneous adipose tissue ( 22589738) Type 2 diabetes ( 32499647)
Interacting Genes		1 interacting genes: EML2	12 interacting genes: BPIFA1 EIF3F EXD1 IFI35 IFT88 PLEKHF2 PTTG2 REL RFC5 SNX32 SPANXA1 SPANXA2
Entrez ID		161829	24139
HPRD ID		14571	16860
Ensembl ID		ENSG00000178997	ENSG00000125746
Uniprot IDs		Q8NHP7	O95834
PDB IDs			4CGB
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Microtubule Polymerization Microtubule Associated Complex Regulation Of Microtubule Nucleation Regulation Of Microtubule Polymerization Tubulin Binding Negative Regulation Of Microtubule Polymerization Or Depolymerization Visual Perception Negative Regulation Of Protein-containing Complex Assembly Sensory Perception Of Sound Negative Regulation Of Supramolecular Fiber Organization Mitotic Spindle Sensory Perception Of Light Stimulus Sensory Perception Of Mechanical Stimulus Negative Regulation Of Cytoskeleton Organization Regulation Of Microtubule Cytoskeleton Organization Regulation Of Microtubule Polymerization Or Depolymerization Spindle Regulation Of Microtubule-based Process Microtubule Binding Microtubule Regulation Of Supramolecular Fiber Organization
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