TOM1L2 and SLC47A2

		TOM1L2	SLC47A2
Description		target of myb1 like 2 membrane trafficking protein	solute carrier family 47 member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Membrane Extracellular Exosome	Plasma Membrane Membrane Apical Plasma Membrane
	Molecular Function	Protein Binding Protein Kinase Binding Clathrin Binding Phosphatidylinositol Binding Ubiquitin Binding	Organic Cation Transmembrane Transporter Activity Antiporter Activity Transmembrane Transporter Activity Xenobiotic Transmembrane Transporter Activity Polyspecific Organic Cation:proton Antiporter Activity
	Biological Process	Signal Transduction Protein Transport Negative Regulation Of Mitotic Nuclear Division	Organic Cation Transport Transmembrane Transport Proton Transmembrane Transport Xenobiotic Detoxification By Transmembrane Export Across The Plasma Membrane
Pathways			SLC-mediated transport of organic cations
Drugs
Diseases
GWAS		Hip index ( 34021172) Schizophrenia ( 25056061 28991256 29483656) TB-LM or TBLH-BMD (pleiotropy) ( 28743860) Total body bone mineral density ( 29304378) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Keratoconus ( 33649486)
Interacting Genes		15 interacting genes: APP BBS4 BBS5 BBS9 FAM9B LAPTM5 MAP3K1 MYO6 NEDD4 RNF11 RNF26 SMURF1 UBC WBP2 WWP2	1 interacting genes: SLC22A2
Entrez ID		146691	146802
HPRD ID		18213	08710
Ensembl ID		ENSG00000175662	ENSG00000180638
Uniprot IDs		B7Z2U2 B7Z671 F5H3S6 Q6ZVM7	Q86VL8
PDB IDs
Enriched GO Terms of Interacting Partners?		BBSome Establishment Of Protein Localization Ciliary Membrane Modification-dependent Protein Catabolic Process Establishment Of Protein Localization To Vacuole Ubiquitin Protein Ligase Activity Potassium Channel Inhibitor Activity Protein Targeting To Vacuole Protein Ubiquitination Negative Regulation Of Potassium Ion Export Across Plasma Membrane Regulation Of Potassium Ion Export Across Plasma Membrane Progesterone Receptor Signaling Pathway Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Protein Transport Protein Localization To Vacuole Receptor Catabolic Process Establishment Of Melanosome Localization Pericentriolar Material Melanosome Transport Pigment Granule Transport Ubiquitin Ligase Complex Post-translational Protein Modification Protein Polyubiquitination Negative Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Catabolic Process Pigment Granule Localization Melanosome Localization Ubiquitin-dependent Protein Catabolic Process Centriolar Satellite Intracellular Protein Localization Protein Targeting To Lysosome Negative Regulation Of Potassium Ion Transport Establishment Of Protein Localization To Organelle Ciliary Transition Zone Protein Localization To Organelle Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Minus-end Directed Microfilament Motor Activity Macromolecule Catabolic Process Vacuolar Transport Formation Of Structure Involved In A Symbiotic Process Induction Of Programmed Cell Death Negative Regulation Of Pre-B Cell Receptor Expression Positive Regulation Of Lysosomal Membrane Permeability Engulfment Of Target By Autophagosome Fructose:sodium Symporter Activity	Acetylcholine Transport Histamine Uptake Pyrimidine Nucleoside Transmembrane Transporter Activity Spermidine Transport Epinephrine Transport Spermidine Transmembrane Transport Putrescine Transport Thiamine Transmembrane Transporter Activity Thiamine Transport Amine Transmembrane Transporter Activity Quaternary Ammonium Group Transmembrane Transporter Activity Spermidine Transmembrane Transporter Activity L-arginine Import Across Plasma Membrane Putrescine Transmembrane Transporter Activity Thiamine Transmembrane Transport Acetylcholine Transmembrane Transporter Activity Serotonin Uptake Choline Transport Norepinephrine Uptake Prostaglandin Transmembrane Transporter Activity Xenobiotic Transport Across Blood-brain Barrier Toxin Transmembrane Transporter Activity Monoamine Transmembrane Transporter Activity Choline Transmembrane Transporter Activity Norepinephrine Transport Polyamine Transmembrane Transport Histamine Transport L-arginine Transmembrane Transporter Activity Organic Cation Transmembrane Transporter Activity Efflux Transmembrane Transporter Activity L-arginine Transmembrane Transport Amine Transport Catecholamine Uptake Dopamine Uptake Azole Transmembrane Transport Serotonin Transport Quaternary Ammonium Group Transport Prostaglandin Transport Pyrimidine-containing Compound Transmembrane Transport L-amino Acid Transmembrane Transporter Activity Neurotransmitter Transmembrane Transporter Activity Basic Amino Acid Transmembrane Transport Vitamin Transmembrane Transport Organic Anion Transmembrane Transporter Activity Dopamine Transport Neurotransmitter Reuptake Basic Amino Acid Transport Xenobiotic Transmembrane Transporter Activity Monoamine Transport Neurotransmitter Uptake
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?