DNHD1 and UBQLNL

		DNHD1	UBQLNL
Description		dynein heavy chain domain 1	ubiquilin like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cilium Dynein Complex Motile Cilium Sperm Flagellum Inner Dynein Arm Cell Projection Extracellular Exosome	Cytosol
	Molecular Function	ATP Binding Minus-end-directed Microtubule Motor Activity Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding	Protein Binding Polyubiquitin Modification-dependent Protein Binding
	Biological Process	Microtubule-based Movement Flagellated Sperm Motility Sperm Flagellum Assembly	Ubiquitin-dependent Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS		DNA methylation (variation) ( 23725790) Malaria ( 31844061)	Malaria ( 31844061)
Interacting Genes		3 interacting genes: BRCA1 PLK1 USP7	3 interacting genes: DESI1 HGS LMNA
Entrez ID		144132	143630
HPRD ID		08137	14472
Ensembl ID		ENSG00000179532	ENSG00000175518
Uniprot IDs		B0I1S4 Q96M86	Q8IYU4
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Regulation Of DNA Metabolic Process Mitotic DNA Integrity Checkpoint Signaling Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Mitotic G2/M Transition Checkpoint P53 Binding Centrosome Cycle Mitotic G2 DNA Damage Checkpoint Signaling Negative Regulation Of Cell Cycle G2/M Phase Transition DNA Repair Mitotic DNA Damage Checkpoint Signaling Microtubule Organizing Center Organization Post-translational Protein Modification Histone H2AK127 Ubiquitin Ligase Activity Recombinational Repair Negative Regulation Of Small Molecule Metabolic Process DNA Metabolic Process Chromosome Segregation DNA Damage Response Regulation Of Cell Cycle G2/M Phase Transition Double-strand Break Repair Via Homologous Recombination Histone H2AK129 Ubiquitin Ligase Activity Protein Modification By Small Protein Conjugation Chromosome Regulation Of G2/M Transition Of Mitotic Cell Cycle BRCA1-BARD1 Complex Signal Transduction In Response To DNA Damage Protein Ubiquitination DNA Damage Checkpoint Signaling Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Synaptonemal Complex Disassembly Golgi Inheritance Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Gene Expression, Epigenetic Regulation Of Ubiquitin-dependent Protein Catabolic Process Symbiont-mediated Disruption Of Host Cell PML Body Protein Metabolic Process Regulation Of Proteasomal Protein Catabolic Process BRCA1-B Complex Negative Regulation Of Mitotic Cell Cycle Double-strand Break Repair Negative Regulation Of Cell Cycle Phase Transition Cellular Response To Indole-3-methanol Regulation Of DNA Repair DNA Recombination Homologous Chromosome Segregation Female Meiosis Chromosome Segregation Regulation Of Chromosome Organization Regulation Of Microtubule-based Process Nuclear Ubiquitin Ligase Complex	Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Lamin Filament DNA Double-strand Break Attachment To Nuclear Envelope Nuclear Transport Nucleocytoplasmic Transport Cellular Localization Protein Transport Establishment Of Protein Localization Ventricular Cardiac Muscle Cell Development Nuclear Pore Localization Establishment Of Protein Localization To Organelle Negative Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Mesenchymal Cell Proliferation Establishment Of Localization In Cell Intracellular Transport Intracellular Protein Transport Structural Constituent Of Nuclear Lamina ESCRT-0 Complex Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Phagocytic Vesicle Lumen Regulation Of Protein Catabolic Process Macromolecule Depalmitoylation DeSUMOylase Activity Importin-alpha Family Protein Binding Palmitoyl-(protein) Hydrolase Activity Protein Desumoylation Inner Dynein Arm Nuclear Lamina Protein Localization To Nuclear Envelope Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Positive Regulation Of Exosomal Secretion Long-chain Fatty Acyl-CoA Hydrolase Activity Minus-end-directed Microtubule Motor Activity Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Intracellular Protein Localization Negative Regulation Of Release Of Cytochrome C From Mitochondria Regulation Of Exosomal Secretion Sperm Flagellum Assembly Regulation Of Cardiac Muscle Hypertrophy In Response To Stress Negative Regulation Of Receptor Signaling Pathway Via JAK-STAT Localization Within Membrane Nuclear Envelope Organization Nuclear Migration Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Ubiquitin-like Protein Ligase Binding Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Macromolecule Deacylation Dynein Light Intermediate Chain Binding Multivesicular Body Membrane Negative Regulation Of Receptor Signaling Pathway Via STAT
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