DNHD1

Description		dynein heavy chain domain 1
Image		No pdb structure
GO Annotations	Cellular Component	Cilium Dynein Complex Motile Cilium Sperm Flagellum Inner Dynein Arm Cell Projection Extracellular Exosome
	Molecular Function	ATP Binding Minus-end-directed Microtubule Motor Activity Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding
	Biological Process	Microtubule-based Movement Flagellated Sperm Motility Sperm Flagellum Assembly
Pathways
Drugs
Diseases
GWAS		DNA methylation (variation) ( 23725790) Malaria ( 31844061)
Novel Interacting Genes		1 novel interacting genes: UBQLNL
Interacting Genes		3 interacting genes: BRCA1 PLK1 USP7
Entrez ID		144132
HPRD ID		08137
Ensembl ID		ENSG00000179532
Uniprot IDs		B0I1S4 Q96M86
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Gene Expression Via Chromosomal CpG Island Methylation Regulation Of DNA Metabolic Process Mitotic DNA Integrity Checkpoint Signaling Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Mitotic G2/M Transition Checkpoint P53 Binding Centrosome Cycle Mitotic G2 DNA Damage Checkpoint Signaling Negative Regulation Of Cell Cycle G2/M Phase Transition DNA Repair Mitotic DNA Damage Checkpoint Signaling Microtubule Organizing Center Organization Post-translational Protein Modification Histone H2AK127 Ubiquitin Ligase Activity Recombinational Repair Negative Regulation Of Small Molecule Metabolic Process DNA Metabolic Process Chromosome Segregation DNA Damage Response Regulation Of Cell Cycle G2/M Phase Transition Double-strand Break Repair Via Homologous Recombination Histone H2AK129 Ubiquitin Ligase Activity Protein Modification By Small Protein Conjugation Chromosome Regulation Of G2/M Transition Of Mitotic Cell Cycle BRCA1-BARD1 Complex Signal Transduction In Response To DNA Damage Protein Ubiquitination DNA Damage Checkpoint Signaling Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Synaptonemal Complex Disassembly Golgi Inheritance Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Gene Expression, Epigenetic Regulation Of Ubiquitin-dependent Protein Catabolic Process Symbiont-mediated Disruption Of Host Cell PML Body Protein Metabolic Process Regulation Of Proteasomal Protein Catabolic Process BRCA1-B Complex Negative Regulation Of Mitotic Cell Cycle Double-strand Break Repair Negative Regulation Of Cell Cycle Phase Transition Cellular Response To Indole-3-methanol Regulation Of DNA Repair DNA Recombination Homologous Chromosome Segregation Female Meiosis Chromosome Segregation Regulation Of Chromosome Organization Regulation Of Microtubule-based Process Nuclear Ubiquitin Ligase Complex
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