POGLUT3 and C11orf65

		POGLUT3	C11orf65
Description		protein O-glucosyltransferase 3	chromosome 11 open reading frame 65
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endomembrane System	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Cytosol Membrane
	Molecular Function	Transferase Activity Glycosyltransferase Activity UDP-glucosyltransferase Activity UDP-xylosyltransferase Activity Glucosyltransferase Activity EGF-domain Serine Glucosyltransferase Activity EGF-domain Serine Xylosyltransferase Activity	Protein Binding
	Biological Process	Protein Glycosylation	Negative Regulation Of Mitochondrial Fission Negative Regulation Of Protein Targeting To Mitochondrion
Pathways
Drugs
Diseases
GWAS			Granulocyte count ( 27863252) Lymphocyte count ( 32888494) Mean corpuscular hemoglobin ( 27863252 29403010) Mean corpuscular volume ( 32888494 29403010) Mean platelet volume ( 32888494) Monocyte percentage of white cells ( 32888494) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252 32888494) Nonunion in individuals with fractures ( 30680360) Platelet count ( 27863252) Platelet distribution width ( 32888494) Red blood cell count ( 32888494) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Uterine fibroids ( 31649266 30194396) White blood cell count ( 27863252 32888494)
Interacting Genes		2 interacting genes: CFTR OGT	7 interacting genes: ATOSB CALM1 CALM2 CALM3 CALML3 DAPK1 SUMO1
Entrez ID		143888	160140
HPRD ID		13773	14579
Ensembl ID		ENSG00000178202	ENSG00000166323
Uniprot IDs		A0A9L9PX09 A0A9L9PY40 Q7Z4H8	Q8NCR3
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Localization Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Positive Regulation Of Anion Channel Activity Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Positive Regulation Of Enamel Mineralization Transepithelial Water Transport Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Positive Regulation Of Monoatomic Anion Transport Membrane Hyperpolarization Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose Carbon Catabolite Regulation Of Transcription Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Protein O-acetylglucosaminyltransferase Activity Negative Regulation Of Protein Targeting To Mitochondrion Negative Regulation Of Mitochondrial Fission Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation Negative Regulation Of Establishment Of Protein Localization To Mitochondrion Amelogenesis Regulation Of Transcription By Glucose ATPase-coupled Inorganic Anion Transmembrane Transporter Activity NSL Complex Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Golgi-associated Vesicle Membrane Intracellular Chemical Homeostasis Cellular Response To Forskolin Regulation Of Establishment Of Protein Localization Regulation Of Cellular Localization Regulation Of Developmental Process Response To Forskolin Chloride Transmembrane Transporter Activity Sperm Capacitation Acetylglucosaminyltransferase Activity Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Sin3-type Complex Cellular Homeostasis Bicarbonate Transport Histone Acetyltransferase Complex Water Transport Negative Regulation Of Stem Cell Population Maintenance Regulation Of Protein Localization To Synapse	Detection Of Calcium Ion Regulation Of Transmembrane Transporter Activity Regulation Of Monoatomic Ion Transmembrane Transporter Activity Negative Regulation Of Transporter Activity Calcineurin-mediated Signaling Presynaptic Cytosol Myelin Sheath Negative Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Transporter Inhibitor Activity Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Calcium Ion Transmembrane Transport Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Negative Regulation Of Cation Transmembrane Transport Titin Binding Regulation Of Calcium Ion Transport Negative Regulation Of Monoatomic Ion Transmembrane Transport Voltage-gated Potassium Channel Complex Regulation Of Cardiac Muscle Contraction Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Cell Communication By Electrical Coupling Regulation Of Monoatomic Cation Transmembrane Transport Protein Phosphatase Activator Activity Calyx Of Held Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Striated Muscle Contraction Negative Regulation Of Monoatomic Ion Transport Catalytic Complex Detection Of Chemical Stimulus Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Response To Metal Ion Negative Regulation Of Transmembrane Transport Calcium Channel Complex Regulation Of Metal Ion Transport Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Sequestering Of Calcium Ion Synaptic Vesicle Membrane Response To Calcium Ion Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Monoatomic Ion Transport Negative Regulation Of Calcium Ion Transmembrane Transport Calcium-mediated Signaling Regulation Of Muscle Contraction Spindle Microtubule Presynaptic Endocytosis Substantia Nigra Development Calcium Channel Regulator Activity Regulation Of Heart Contraction
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