NRSN1 and PLS3

		NRSN1	PLS3
Description		neurensin 1	plastin 3
Image		No pdb structure
GO Annotations	Cellular Component	Membrane Transport Vesicle Growth Cone Cytoplasmic Vesicle Cell Projection Neuron Projection Neuronal Cell Body	Cytoplasm Cytosol Actin Filament Plasma Membrane Neuromuscular Junction Actin Filament Bundle
	Molecular Function	Protein Binding	Actin Binding Calcium Ion Binding Metal Ion Binding Actin Filament Binding Structural Constituent Of Presynaptic Actin Cytoskeleton
	Biological Process	Nervous System Development	Actin Filament Bundle Assembly Actin Filament Network Formation Bone Development Regulation Of Synaptic Vesicle Cycle Presynaptic Actin Cytoskeleton Organization
Pathways
Drugs
Diseases
GWAS		Alzheimer's disease in hypertension ( 31055733) Coronary artery disease ( 32469254) Information processing speed ( 21130836) Initial pursuit acceleration ( 29064472) Liver enzyme levels (alkaline phosphatase) ( 33972514) Periodontitis (Mean PAL) ( 24024966) Squamous cell lung carcinoma ( 28604730) Type 2 diabetes ( 31049640)	Gestational age at birth (maternal effect) ( 28877031) Mean platelet volume ( 32888494) Platelet count ( 32888494) Platelet distribution width ( 32888494) Preterm birth (maternal effect) ( 28877031)
Interacting Genes		8 interacting genes: FATE1 FCGR1A GPA33 LYVE1 RNF24 SPACA1 SPINK1 TMEM106C	5 interacting genes: APP ATXN2 FILNC1 OGT SNCA
Entrez ID		140767	5358
HPRD ID		18285	02133
Ensembl ID		ENSG00000152954	ENSG00000102024
Uniprot IDs		Q8IZ57	B4DPW9 P13797
PDB IDs			1AOA 1WJO 7R94 7SX8 7SX9 7SXA
Enriched GO Terms of Interacting Partners?			Growth Cone Amyloid-beta Complex Regulation Of Synapse Assembly Growth Cone Lamellipodium Regulation Of Presynapse Organization Response To Copper Ion Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Neuron Differentiation Regulation Of Presynapse Assembly Regulation Of Protein Catabolic Process Amyloid Fibril Formation Regulation Of Neurotransmitter Uptake Microglial Cell Activation Regulation Of Generation Of Precursor Metabolites And Energy Leukocyte Activation Involved In Inflammatory Response Cellular Response To Copper Ion Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Cysteine-type Endopeptidase Inhibitor Activity Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Neuron Differentiation
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