MICOS13 and HSFX1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MICOS13	HSFX1
Description		mitochondrial contact site and cristae organizing system subunit 13	heat shock transcription factor family, X-linked 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	SAM Complex Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Membrane Mitochondrial Crista Junction MICOS Complex MIB Complex	Chromatin Nucleus Cytoplasm
	Molecular Function	Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding
	Biological Process	Inner Mitochondrial Membrane Organization Cristae Formation	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways		Cristae formation
Drugs
Diseases
GWAS
Interacting Genes		11 interacting genes: ACSF2 APOC1 APOC2 APOC4 DIABLO HSFX1 HSFX2 PBX3 RHBDD2 TEX44 UBC	12 interacting genes: AGTRAP ATXN1 ATXN1L CACFD1 DIABLO KRTAP12-2 MAL2 MICOS13 MTIF3 RBFOX1 SDR16C5 SYP
Entrez ID		125988	100506164
HPRD ID		15198
Ensembl ID		ENSG00000174917	ENSG00000171116
Uniprot IDs		A0A140TA84 A0A140TA86 Q5XKP0	A0A140VK21 Q9UBD0
PDB IDs
Enriched GO Terms of Interacting Partners?		High-density Lipoprotein Particle Very-low-density Lipoprotein Particle Acylglycerol Homeostasis Negative Regulation Of Very-low-density Lipoprotein Particle Clearance Triglyceride Homeostasis Chylomicron Remnant Clearance Triglyceride-rich Lipoprotein Particle Clearance Regulation Of Phospholipid Catabolic Process Lipase Inhibitor Activity Chylomicron Phospholipid Efflux Negative Regulation Of Lipoprotein Particle Clearance Negative Regulation Of Cholesterol Transport Plasma Lipoprotein Particle Clearance Lipid Homeostasis Cholesterol Efflux Negative Regulation Of Receptor-mediated Endocytosis Lipoprotein Metabolic Process Regulation Of Phospholipid Metabolic Process Plasma Lipoprotein Particle Remodeling Protein-containing Complex Remodeling Negative Regulation Of Lipid Transport Regulation Of Triglyceride Metabolic Process Regulation Of Fatty Acid Biosynthetic Process Negative Regulation Of Phosphatidylcholine Catabolic Process Posterior Compartment Specification Anterior Compartment Pattern Formation Regulation Of Lipid Catabolic Process Regulation Of Cholesterol Transport Cholesterol Transport Negative Regulation Of Endocytosis Lipid Transport Sterol Transport Positive Regulation Of Very-low-density Lipoprotein Particle Remodeling Phospholipid Transport Regulation Of Fatty Acid Metabolic Process Regulation Of Phosphatidylcholine Catabolic Process Positive Regulation Of Phospholipid Catabolic Process Lipoprotein Lipase Activator Activity Negative Regulation Of Lipid Metabolic Process Chylomicron Remodeling Compartment Pattern Specification Regulation Of Receptor-mediated Endocytosis Very-low-density Lipoprotein Particle Clearance Regulation Of Ketone Metabolic Process Intermediate-density Lipoprotein Particle Dorsal Spinal Cord Development Sequence-specific DNA Binding Phosphatidylcholine-sterol O-acyltransferase Activator Activity Organophosphate Ester Transport	POZ Domain Binding
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