SLC5A10 and TOM1L2

		SLC5A10	TOM1L2
Description		solute carrier family 5 member 10	target of myb1 like 2 membrane trafficking protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Apical Plasma Membrane Extracellular Exosome	Endosome Membrane Extracellular Exosome
	Molecular Function	D-glucose:sodium Symporter Activity Solute:sodium Symporter Activity Transmembrane Transporter Activity Mannose:sodium Symporter Activity Fructose:sodium Symporter Activity	Protein Binding Protein Kinase Binding Clathrin Binding Phosphatidylinositol Binding Ubiquitin Binding
	Biological Process	Monoatomic Ion Transport Sodium Ion Transport Hexose Transmembrane Transport Fructose Transmembrane Transport Mannose Transmembrane Transport Sodium Ion Transmembrane Transport Transmembrane Transport	Signal Transduction Protein Transport Negative Regulation Of Mitotic Nuclear Division
Pathways		Cellular hexose transport
Drugs
Diseases
GWAS		1,5-anhydroglucitol levels ( 28588231)	Hip index ( 34021172) Schizophrenia ( 25056061 28991256 29483656) TB-LM or TBLH-BMD (pleiotropy) ( 28743860) Total body bone mineral density ( 29304378) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes			15 interacting genes: APP BBS4 BBS5 BBS9 FAM9B LAPTM5 MAP3K1 MYO6 NEDD4 RNF11 RNF26 SMURF1 UBC WBP2 WWP2
Entrez ID		125206	146691
HPRD ID		15394	18213
Ensembl ID		ENSG00000154025	ENSG00000175662
Uniprot IDs		A0PJK1	B7Z2U2 B7Z671 F5H3S6 Q6ZVM7
PDB IDs
Enriched GO Terms of Interacting Partners?		Clathrin Binding Negative Regulation Of Mitotic Nuclear Division Ubiquitin Binding Regulation Of Mitotic Nuclear Division Phosphatidylinositol Binding Regulation Of Nuclear Division	BBSome Establishment Of Protein Localization Ciliary Membrane Modification-dependent Protein Catabolic Process Establishment Of Protein Localization To Vacuole Ubiquitin Protein Ligase Activity Potassium Channel Inhibitor Activity Protein Targeting To Vacuole Protein Ubiquitination Negative Regulation Of Potassium Ion Export Across Plasma Membrane Regulation Of Potassium Ion Export Across Plasma Membrane Progesterone Receptor Signaling Pathway Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Protein Transport Protein Localization To Vacuole Receptor Catabolic Process Establishment Of Melanosome Localization Pericentriolar Material Melanosome Transport Pigment Granule Transport Ubiquitin Ligase Complex Post-translational Protein Modification Protein Polyubiquitination Negative Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Catabolic Process Pigment Granule Localization Melanosome Localization Ubiquitin-dependent Protein Catabolic Process Centriolar Satellite Intracellular Protein Localization Protein Targeting To Lysosome Negative Regulation Of Potassium Ion Transport Establishment Of Protein Localization To Organelle Ciliary Transition Zone Protein Localization To Organelle Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Minus-end Directed Microfilament Motor Activity Macromolecule Catabolic Process Vacuolar Transport Formation Of Structure Involved In A Symbiotic Process Induction Of Programmed Cell Death Negative Regulation Of Pre-B Cell Receptor Expression Positive Regulation Of Lysosomal Membrane Permeability Engulfment Of Target By Autophagosome Fructose:sodium Symporter Activity
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