SEZ6 and CHDH

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		SEZ6	CHDH
Description		seizure related 6 homolog	choline dehydrogenase
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Membrane Neuronal Cell Body Dendritic Spine Dendritic Shaft Perinuclear Region Of Cytoplasm Apical Dendrite	Mitochondrion Mitochondrial Inner Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding Choline Dehydrogenase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On CH-OH Group Of Donors Flavin Adenine Dinucleotide Binding
	Biological Process	Adult Locomotory Behavior Cerebellar Purkinje Cell Layer Development Regulation Of Dendrite Development Synapse Maturation Excitatory Postsynaptic Potential	Glycine Betaine Biosynthetic Process From Choline Choline Catabolic Process
Pathways			Choline catabolism
Drugs
Diseases
GWAS		Language functional connectivity ( 34929384) Mean arterial pressure ( 27618448)	Axial length ( 24144296) Body mass index ( 26426971) interleukin 17 receptor B levels ( 25147954) Medication use (calcium channel blockers) ( 31015401) Refractive error ( 32231278) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		3 interacting genes: CHDH TNK2 UBQLN2	3 interacting genes: NOTCH2NLA RPL8 SEZ6
Entrez ID		124925	55349
HPRD ID		18041	13050
Ensembl ID		ENSG00000063015	ENSG00000016391
Uniprot IDs		Q53EL9	Q8NE62
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Clathrin-dependent Endocytosis Regulation Of Receptor-mediated Endocytosis Grb2-EGFR Complex Negative Regulation Of G Protein-coupled Receptor Internalization Glycine Betaine Biosynthetic Process From Choline Choline Dehydrogenase Activity Cytoophidium Negative Regulation Of Clathrin-dependent Endocytosis Oxidoreductase Activity, Acting On CH-OH Group Of Donors Choline Catabolic Process Regulation Of Endocytosis Choline Metabolic Process GTPase Inhibitor Activity Regulation Of Vesicle-mediated Transport Positive Regulation Of ERAD Pathway Negative Regulation Of Receptor Internalization Amino-acid Betaine Metabolic Process WW Domain Binding Regulation Of ERAD Pathway Protein Serine/threonine/tyrosine Kinase Activity Negative Regulation Of Receptor-mediated Endocytosis Epidermal Growth Factor Receptor Binding Positive Regulation Of Protein Metabolic Process Cytoplasmic Vesicle Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Non-membrane Spanning Protein Tyrosine Kinase Activity Regulation Of Autophagosome Assembly Molecular Condensate Scaffold Activity Positive Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Vacuole Organization Flavin Adenine Dinucleotide Binding
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