ERP27 and EEF1D

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ERP27	EEF1D
Gene Name		endoplasmic reticulum protein 27	eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Cell Surface	Nucleus Nucleolus Cytoplasm Cytosol Eukaryotic Translation Elongation Factor 1 Complex
	Molecular Function	Protein Disulfide Isomerase Activity	DNA Binding Translation Elongation Factor Activity Signal Transducer Activity Protein Binding Translation Factor Activity, Nucleic Acid Binding
	Biological Process	Protein Folding Response To Endoplasmic Reticulum Stress	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Translation Translational Elongation Signal Transduction Gene Expression Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Cellular Protein Metabolic Process
Pathways			Translation Eukaryotic Translation Elongation
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: EEF1D PDIA3 SGTA UBQLN1 UBQLN4	33 interactors: ARHGAP21 ASCC2 ATG7 CAMSAP2 CD48 CDK1 CRMP1 CSNK2A1 CTBP1 CTBP2 ECH1 EEF1G EPRS ERP27 FOS FRA10AC1 GARS HEXDC KARS KTN1 MAP1B NR2F1 POT1 PRKCA RELA RPS6KA1 SIAH1 SIAH2 SQSTM1 TERF1 TINF2 TPT1 VARS
Entrez ID		121506	1936
HPRD ID		08723	00560
Ensembl ID			ENSG00000104529
Uniprot IDs		F5GYS6 Q96DN0	B2RAR6 D3DWK1 P29692
PDB IDs		2L4C 4F9Z
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Chromosome Organization Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Protein Metabolic Process Movement Of Cell Or Subcellular Component Response To External Stimulus Negative Regulation Of Telomere Maintenance Regulation Of Chromosome Organization Axonogenesis Regulation Of Telomere Maintenance Via Telomerase Axon Development Negative Regulation Of Cellular Protein Metabolic Process Cell Morphogenesis Involved In Neuron Differentiation Toll-like Receptor 5 Signaling Pathway Negative Regulation Of Cellular Metabolic Process Toll-like Receptor 10 Signaling Pathway Cell Differentiation Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Regulation Of Apoptotic Process Neuron Projection Morphogenesis Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Regulation Of Protein Metabolic Process TRIF-dependent Toll-like Receptor Signaling Pathway Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death MyD88-independent Toll-like Receptor Signaling Pathway Diadenosine Tetraphosphate Biosynthetic Process Regulation Of Telomere Maintenance Toll-like Receptor 3 Signaling Pathway Regulation Of Cell Death Cellular Macromolecule Biosynthetic Process MyD88-dependent Toll-like Receptor Signaling Pathway Viral Genome Replication Cell Morphogenesis Involved In Differentiation Negative Regulation Of Cell Death Macromolecule Biosynthetic Process Regulation Of Cellular Protein Metabolic Process Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Biosynthetic Process Regulation Of Schwann Cell Differentiation Neuron Projection Development Neurotrophin TRK Receptor Signaling Pathway Cell Projection Morphogenesis Nucleobase-containing Compound Metabolic Process Axon Guidance Chemotaxis Neurotrophin Signaling Pathway Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Histone H4 Acetylation
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