TAGAP and OSTCP1

		TAGAP	OSTCP1
Description		T cell activation RhoGTPase activating protein	oligosaccharyltransferase complex subunit pseudogene 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity GTPase Activator Activity Protein Binding
	Biological Process	Signal Transduction Regulation Of Rho Protein Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction
Pathways		RHOA GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		Autoimmune traits (pleiotropy) ( 30572963) Bladder cancer (smoking interaction) ( 24662972) Celiac disease ( 20190752 30572963 25920553 24999842 18311140 22057235) Celiac disease and Rheumatoid arthritis ( 26546613) Crohn's disease ( 23128233 21102463) Crohn's disease and celiac disease ( 21298027) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Lipoprotein (a) - cholesterol levels ( 25575512) Lipoprotein (a) levels ( 26377243) Multiple sclerosis ( 21833088 22190364 24076602 31604244) Psoriasis ( 23143594) Rheumatoid arthritis ( 24390342 30423114) Rheumatoid arthritis (ACPA-positive) ( 24532676 23143596) Systemic lupus erythematosus ( 28714469) Type 1 diabetes ( 34127860)	Refractive error ( 32231278)
Interacting Genes		1 interacting genes: HSF2BP	4 interacting genes: APP EDA LMNA SYNE4
Entrez ID		117289	202459
HPRD ID		18143	14130
Ensembl ID		ENSG00000164691	ENSG00000293101
Uniprot IDs		Q8N103
PDB IDs
Enriched GO Terms of Interacting Partners?		Double-strand Break Repair Involved In Meiotic Recombination Female Meiosis I Toxic Substance Binding Radial Spoke Head	Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Regulation Of Extrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Non-canonical NF-kappaB Signal Transduction Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Regulation Of Protein Localization To Nucleus Growth Factor Receptor Binding Main Axon Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Hair Follicle Placode Formation Trachea Gland Development Salivary Gland Cavitation Death Receptor Agonist Activity Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Lamin Filament DNA Double-strand Break Attachment To Nuclear Envelope Nuclear Pore Localization Structural Constituent Of Nuclear Lamina Establishment Or Maintenance Of Cell Polarity Nuclear Envelope Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Regulation Of Canonical Wnt Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity
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