LRRC3B and CD37

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LRRC3B	CD37
Description		leucine rich repeat containing 3B	CD37 molecule
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Immunological Synapse Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	Protein Binding Signaling Receptor Activity	Protein Binding
	Biological Process		Positive Regulation Of Immunoglobulin Production Regulation Of Humoral Immune Response Negative Regulation Of Myeloid Dendritic Cell Activation T Cell Proliferation Negative Regulation Of T Cell Proliferation Defense Response To Protozoan Regulation Of Defense Response To Virus
Pathways
Drugs			Otlertuzumab
Diseases
GWAS		Longevity (100 years and older) ( 33948810) Sensorimotor dexterity ( 31596458) Waist-hip ratio ( 28552196)
Interacting Genes		7 interacting genes: CD37 EMP1 LNX1 MS4A13 TMEM220 TMEM60 YIPF6	6 interacting genes: AGTR1 CD53 EMP1 GJB1 LHFPL5 LRRC3B
Entrez ID		116135	951
HPRD ID		14318	01053
Ensembl ID		ENSG00000179796	ENSG00000104894
Uniprot IDs		Q96PB8	P11049
PDB IDs		5EMA
Enriched GO Terms of Interacting Partners?			Angiotensin Type I Receptor Activity Plasma Membrane Phospholipase C-activating Angiotensin-activated Signaling Pathway Bradykinin Receptor Binding Renin-angiotensin Regulation Of Aldosterone Production Angiotensin Type II Receptor Activity Maintenance Of Blood Vessel Diameter Homeostasis By Renin-angiotensin Positive Regulation Of Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Regulation Of Renal Sodium Excretion Membrane Bleb Assembly Gap Junction Assembly Detection Of Mechanical Stimulus Involved In Sensory Perception Of Sound Stereocilium Bundle
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