VPS26B and CD276

		VPS26B	CD276
Description		VPS26 retromer complex component B	CD276 molecule
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Early Endosome Late Endosome Cytosol Membrane Retromer Complex Retromer, Cargo-selective Complex Phagocytic Vesicle Postsynaptic Recycling Endosome Postsynaptic Early Endosome Glutamatergic Synapse	External Side Of Plasma Membrane Membrane
	Molecular Function	Protein Binding	Signaling Receptor Binding Protein Binding
	Biological Process	Intracellular Protein Transport Protein Transport Regulation Of Macroautophagy Retrograde Transport, Endosome To Golgi Cellular Response To Type II Interferon Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane	Regulation Of Cytokine Production Positive Regulation Of Cytokine Production Regulation Of Type II Interferon Production Positive Regulation Of Type II Interferon Production Positive Regulation Of T Cell Proliferation T Cell Activation Regulation Of Immune Response T Cell Receptor Signaling Pathway
Pathways
Drugs			Omburtamab
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Verbal declarative memory ( 25648963)	Alanine aminotransferase levels ( 33547301 34315874) Aspartate aminotransferase levels ( 33547301 34315874) Bipolar disorder ( 21738484 31043756) Cold medicine-related Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) with severe ocular complications ( 28100913) Gamma glutamyl transferase levels ( 29403010 33339817) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (gamma-glutamyl transferase) ( 22001757 33972514) Tourette syndrome ( 30818990)
Interacting Genes		2 interacting genes: NPLOC4 VPS35
Entrez ID		112936	80381
HPRD ID		14395	05756
Ensembl ID		ENSG00000151502	ENSG00000103855
Uniprot IDs		Q4G0F5	A0A0C4DGH0 A8K9J6 Q5ZPR3
PDB IDs
Enriched GO Terms of Interacting Partners?		Poly(C) RNA Binding Nuclear Outer Membrane-endoplasmic Reticulum Membrane Network UFD1-NPL4 Complex Positive Regulation Of Locomotion Involved In Locomotory Behavior Negative Regulation Of Protein Homooligomerization Mitochondrion-derived Vesicle Positive Regulation Of Wnt Protein Secretion Negative Regulation Of Late Endosome To Lysosome Transport Retromer, Cargo-selective Complex Positive Regulation Of Dopamine Biosynthetic Process Regulation Of Terminal Button Organization Regulation Of Dopamine Biosynthetic Process Mitochondrion To Lysosome Vesicle-mediated Transport Negative Regulation Of Protein Oligomerization Regulation Of Locomotion Involved In Locomotory Behavior Tubular Endosome Negative Regulation Of Lysosomal Protein Catabolic Process Positive Regulation Of Dopamine Metabolic Process Positive Regulation Of Dopamine Receptor Signaling Pathway Voluntary Musculoskeletal Movement Negative Regulation Of RIG-I Signaling Pathway D1 Dopamine Receptor Binding VCP-NPL4-UFD1 AAA ATPase Complex Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport, Endosome To Plasma Membrane K48-linked Polyubiquitin Modification-dependent Protein Binding Establishment Of Protein Localization To Postsynaptic Membrane Neurotransmitter Receptor Transport To Postsynaptic Membrane Regulation Of Lysosomal Protein Catabolic Process Regulation Of Dopamine Receptor Signaling Pathway Neurotransmitter Receptor Transport To Plasma Membrane Mitochondrial Fragmentation Involved In Apoptotic Process Dopaminergic Synapse Regulation Of Dendritic Spine Maintenance Musculoskeletal Movement Endosome To Plasma Membrane Protein Transport Protein Localization To Endosome Neurotransmitter Receptor Transport Retrograde Protein Transport, ER To Cytosol Poly(A) Binding Regulation Of RIG-I Signaling Pathway Transcytosis Regulation Of Dopamine Metabolic Process Positive Regulation Of Mitochondrial Fission Retromer Complex Poly(U) RNA Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression K63-linked Polyubiquitin Modification-dependent Protein Binding Intracellular Protein Transport
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?