VPS26B

Description		VPS26 retromer complex component B
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Early Endosome Late Endosome Cytosol Membrane Retromer Complex Retromer, Cargo-selective Complex Phagocytic Vesicle Postsynaptic Recycling Endosome Postsynaptic Early Endosome Glutamatergic Synapse
	Molecular Function	Protein Binding
	Biological Process	Intracellular Protein Transport Protein Transport Regulation Of Macroautophagy Retrograde Transport, Endosome To Golgi Cellular Response To Type II Interferon Regulation Of Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane
Pathways
Drugs
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Verbal declarative memory ( 25648963)
Novel Interacting Genes		2 novel interacting genes: CD276 PABPC4
Interacting Genes		2 interacting genes: NPLOC4 VPS35
Entrez ID		112936
HPRD ID		14395
Ensembl ID		ENSG00000151502
Uniprot IDs		Q4G0F5
PDB IDs
Enriched GO Terms of Interacting Partners?		Poly(C) RNA Binding Nuclear Outer Membrane-endoplasmic Reticulum Membrane Network UFD1-NPL4 Complex Positive Regulation Of Locomotion Involved In Locomotory Behavior Negative Regulation Of Protein Homooligomerization Mitochondrion-derived Vesicle Positive Regulation Of Wnt Protein Secretion Negative Regulation Of Late Endosome To Lysosome Transport Retromer, Cargo-selective Complex Positive Regulation Of Dopamine Biosynthetic Process Regulation Of Terminal Button Organization Regulation Of Dopamine Biosynthetic Process Mitochondrion To Lysosome Vesicle-mediated Transport Negative Regulation Of Protein Oligomerization Regulation Of Locomotion Involved In Locomotory Behavior Tubular Endosome Negative Regulation Of Lysosomal Protein Catabolic Process Positive Regulation Of Dopamine Metabolic Process Positive Regulation Of Dopamine Receptor Signaling Pathway Voluntary Musculoskeletal Movement Negative Regulation Of RIG-I Signaling Pathway D1 Dopamine Receptor Binding VCP-NPL4-UFD1 AAA ATPase Complex Neurotransmitter Receptor Transport, Endosome To Postsynaptic Membrane Neurotransmitter Receptor Transport, Endosome To Plasma Membrane K48-linked Polyubiquitin Modification-dependent Protein Binding Establishment Of Protein Localization To Postsynaptic Membrane Neurotransmitter Receptor Transport To Postsynaptic Membrane Regulation Of Lysosomal Protein Catabolic Process Regulation Of Dopamine Receptor Signaling Pathway Neurotransmitter Receptor Transport To Plasma Membrane Mitochondrial Fragmentation Involved In Apoptotic Process Dopaminergic Synapse Regulation Of Dendritic Spine Maintenance Musculoskeletal Movement Endosome To Plasma Membrane Protein Transport Protein Localization To Endosome Neurotransmitter Receptor Transport Retrograde Protein Transport, ER To Cytosol Poly(A) Binding Regulation Of RIG-I Signaling Pathway Transcytosis Regulation Of Dopamine Metabolic Process Positive Regulation Of Mitochondrial Fission Retromer Complex Poly(U) RNA Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression K63-linked Polyubiquitin Modification-dependent Protein Binding Intracellular Protein Transport
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