L3HYPDH and PCNX4

		L3HYPDH	PCNX4
Description		trans-L-3-hydroxyproline dehydratase	pecanex 4
Image			No pdb structure
GO Annotations	Cellular Component		Membrane
	Molecular Function	Lyase Activity Hydro-lyase Activity Proline Racemase Activity Trans-L-3-hydroxyproline Dehydratase Activity	Protein Binding
	Biological Process
Pathways
Drugs		Proline
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545)	Appendicular lean mass ( 33097823)
Interacting Genes			4 interacting genes: CEP63 DISC1 FBP1 MTNR1B
Entrez ID		112849	64430
HPRD ID		08065	16604
Ensembl ID		ENSG00000126790	ENSG00000126773
Uniprot IDs		Q96EM0	B6ZDM2 Q63HM2
PDB IDs		7QPO
Enriched GO Terms of Interacting Partners?			Cellular Hypotonic Salinity Response Hyperosmotic Salinity Response Cellular Hyperosmotic Salinity Response Phosphoric Ester Hydrolase Activity Cellular Response To Raffinose Cellular Response To Magnesium Ion Fructose 1,6-bisphosphate 1-phosphatase Activity Melatonin Receptor Activity Positive Regulation Of Circadian Sleep/wake Cycle, Sleep Negative Regulation Of CGMP-mediated Signaling Regulation Of Neuronal Action Potential Negative Regulation Of Transmission Of Nerve Impulse Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Radial Glia-guided Pyramidal Neuron Migration Pyramidal Neuron Migration To Cerebral Cortex Molecular Adaptor Activity Central Region Of Growth Cone Negative Regulation Of Protein K63-linked Ubiquitination De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation De Novo Centriole Assembly Proline Racemase Activity Trans-L-3-hydroxyproline Dehydratase Activity Hydro-lyase Activity Fructose 1,6-bisphosphate Metabolic Process Monosaccharide Binding Positive Regulation Of Transmission Of Nerve Impulse Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep Cerebral Cortex Radial Glia-guided Migration Negative Regulation Of Protein Polyubiquitination Cellular Hypotonic Response Cellular Response To Salt Stress Cellular Response To Phorbol 13-acetate 12-myristate Ciliary Basal Body Hypotonic Response AMP Binding Response To Phorbol 13-acetate 12-myristate Negative Regulation Of Vasoconstriction Regulation Of CGMP-mediated Signaling Fructose Metabolic Process Fructose 6-phosphate Metabolic Process Regulation Of Protein K63-linked Ubiquitination Cell Proliferation In Forebrain Regulation Of Cell Growth Cellular Hyperosmotic Response Response To Magnesium Ion Negative Regulation Of Glycolytic Process Response To Salt Stress Positive Regulation Of Circadian Rhythm Negative Regulation Of Nervous System Process Regulation Of Transmission Of Nerve Impulse
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