RWDD2A and SNAP91

		RWDD2A	SNAP91
Description		RWD domain containing 2A	synaptosome associated protein 91
Image			No pdb structure
GO Annotations	Cellular Component		Plasma Membrane Clathrin-coated Pit Synaptic Vesicle Membrane Clathrin-coated Vesicle Extrinsic Component Of Presynaptic Endocytic Zone Membrane
	Molecular Function	Protein Binding	SNARE Binding Protein Binding Phospholipid Binding 1-phosphatidylinositol Binding Phosphatidylinositol-4,5-bisphosphate Binding Protein Kinase Binding Clathrin Binding Clathrin Heavy Chain Binding
	Biological Process		Vesicle Budding From Membrane Protein Transport Regulation Of Receptor-mediated Endocytosis Clathrin Coat Assembly Clathrin-dependent Endocytosis Regulation Of Clathrin-dependent Endocytosis
Pathways			Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS			Age-related hearing impairment ( 34108613) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Bipolar disorder with mood-incongruent psychosis ( 23092984) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Electrodermal activity ( 25387706) Macular thickness ( 30535121) Refractive error ( 32231278) Schizophrenia ( 28991256 29483656 30285260)
Interacting Genes		4 interacting genes: ARHGEF6 ERBB3 MCMBP PSMB1	15 interacting genes: ABI2 AP2A2 AP2B1 DNAJC5 EPS15 ERBB2 ERBB3 ERBB4 GEM MIPOL1 NECAP1 OGT PLCG1 TRAF3IP1 TUBA1B
Entrez ID		112611	9892
HPRD ID		15287	06391
Ensembl ID		ENSG00000013392	ENSG00000065609
Uniprot IDs		B2R7R2 B4DZK9 Q9UIY3	B7Z2N2 E9PDG8 O60641
PDB IDs		2DAW
Enriched GO Terms of Interacting Partners?			Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Postsynaptic Neurotransmitter Receptor Internalization Vesicle-mediated Transport In Synapse AP-2 Adaptor Complex Epidermal Growth Factor Receptor Signaling Pathway Basal Plasma Membrane Clathrin-coated Pit ERBB3:ERBB2 Complex ERBB Signaling Pathway ERBB2 Signaling Pathway Neuregulin Receptor Activity ErbB-3 Class Receptor Binding ERBB2-ERBB4 Signaling Pathway Presynaptic Endocytosis Cellular Response To Epidermal Growth Factor Stimulus Peptidyl-tyrosine Phosphorylation Response To Epidermal Growth Factor Postsynaptic Endocytic Zone ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway ERBB4 Signaling Pathway Positive Regulation Of Epithelial Cell Proliferation Receptor Internalization Clathrin Adaptor Complex Neuromuscular Junction Clathrin Adaptor Activity Endolysosome Membrane Heart Development Schwann Cell Development Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane Post-anal Tail Morphogenesis Cytoplasmic Side Of Plasma Membrane Clathrin Coat Assembly Clathrin-coated Endocytic Vesicle Protein Tyrosine Kinase Activity Peripheral Nervous System Development Membrane Coat Clathrin-dependent Endocytosis Protein Localization To Postsynaptic Membrane Protein Localization To Postsynapse Regulation Of Epithelial Cell Proliferation Cellular Localization Establishment Of Localization In Cell Receptor-mediated Endocytosis Synaptic Vesicle Endocytosis Endocytosis Growth Factor Binding Receptor Complex Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Establishment Of Planar Polarity Involved In Nephron Morphogenesis
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