GPR45 and SULT1C4

		GPR45	SULT1C4
Description		G protein-coupled receptor 45	sulfotransferase family 1C member 4
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Cytoplasm Cytosol
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding	Aryl Sulfotransferase Activity Sulfotransferase Activity Transferase Activity
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway	Ethanol Catabolic Process Xenobiotic Metabolic Process Flavonoid Metabolic Process Doxorubicin Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation
Pathways		G alpha (s) signalling events	Cytosolic sulfonation of small molecules Paracetamol ADME
Drugs			Ritodrine
Diseases
GWAS		Body mass index ( 26426971) Menarche (age at onset) ( 25231870 27182965)	Eyebrow thickness ( 26926045) Urinary albumin-to-creatinine ratio ( 32600054)
Interacting Genes		1 interacting genes: OTX2
Entrez ID		11250	27233
HPRD ID		05325	07461
Ensembl ID		ENSG00000135973	ENSG00000198075
Uniprot IDs		B5B0C1 Q9Y5Y3	O75897 Q6PD90
PDB IDs			2AD1 2GWH
Enriched GO Terms of Interacting Partners?		Primitive Streak Formation Positive Regulation Of Embryonic Development Eukaryotic Initiation Factor 4E Binding Positive Regulation Of Gastrulation Regulation Of Gastrulation Doxorubicin Metabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Ethanol Metabolic Process Flavonoid Metabolic Process Sulfation Aryl Sulfotransferase Activity Ethanol Catabolic Process Error-free Translesion Synthesis Deoxycytidyl Transferase Activity Error-prone Translesion Synthesis DNA-directed DNA Polymerase Activity Translesion Synthesis Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Midbrain Development Dopaminergic Neuron Differentiation Alcohol Catabolic Process Postreplication Repair Sulfotransferase Activity Phosphatidylinositol-3,4,5-trisphosphate Binding DNA Synthesis Involved In DNA Repair Secondary Metabolic Process
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