PRRT2 and SMIM5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PRRT2	SMIM5
Description		proline rich transmembrane protein 2	small integral membrane protein 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Synaptic Vesicle Membrane Axon Synaptic Vesicle Membrane Cytoplasmic Vesicle Vesicle Presynaptic Membrane Cell Projection Dendritic Spine Axon Terminus Synapse Postsynaptic Membrane Presynapse Postsynaptic Density Membrane Glutamatergic Synapse	Membrane
	Molecular Function	Protein Binding Syntaxin-1 Binding	Protein Binding
	Biological Process	Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Negative Regulation Of SNARE Complex Assembly Neuromuscular Process Controlling Posture Regulation Of Calcium-dependent Activation Of Synaptic Vesicle Fusion Negative Regulation Of Short-term Synaptic Potentiation
Pathways
Drugs
Diseases
GWAS
Interacting Genes		8 interacting genes: AQP6 F2RL1 GPRC5D SLC10A6 SLC71A2 SMIM5 SNAP25 TLCD4	7 interacting genes: ARFIP1 EHHADH PRRT2 RBFA SGTA SH3GLB1 ZFYVE21
Entrez ID		112476	643008
HPRD ID		13995
Ensembl ID		ENSG00000167371	ENSG00000204323
Uniprot IDs		Q7Z6L0	Q71RC9
PDB IDs
Enriched GO Terms of Interacting Partners?			Long-chain (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity Intramolecular Oxidoreductase Activity, Transposing C=C Bonds TRC Complex Negative Regulation Of Retrograde Transport, Endosome To Golgi Protein Localization To Vacuolar Membrane Negative Regulation Of Short-term Synaptic Potentiation Negative Regulation Of SNARE Complex Assembly Regulation Of Calcium-dependent Activation Of Synaptic Vesicle Fusion Delta(3)-delta(2)-enoyl-CoA Isomerase Activity BAT3 Complex Binding 'de Novo' Post-translational Protein Folding Positive Regulation Of Membrane Tubulation Negative Regulation Of Vesicle Fusion Autophagic Cell Death Enoyl-CoA Hydratase Activity (3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity Negative Regulation Of ERAD Pathway Regulation Of Retrograde Transport, Endosome To Golgi Phosphatidylinositol 3-kinase Activator Activity 3-hydroxyacyl-CoA Dehydratase Activity
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