CEP43 and LINC01558

		CEP43	LINC01558
Description		centrosomal protein 43	long intergenic non-protein coding RNA 1558
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Centrosome Centriole Microtubule Organizing Center Cytosol Cytoskeleton Microtubule Cytoskeleton Cell Projection Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Protein Kinase Binding Protein Tyrosine Kinase Inhibitor Activity Protein Homodimerization Activity
	Biological Process	Negative Regulation Of Protein Kinase Activity Positive Regulation Of Cell Population Proliferation Cell Projection Organization Positive Regulation Of Cell Growth Positive Regulation Of Cell Migration Microtubule Anchoring
Pathways		Signaling by cytosolic FGFR1 fusion mutants Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane Signaling by FGFR1 in disease AURKA Activation by TPX2
Drugs
Diseases
GWAS			Heel bone mineral density ( 30598549)
Interacting Genes		4 interacting genes: NAGK OGT PPP2R1B S100A6	1 interacting genes: PTPN11
Entrez ID		11116	26238
HPRD ID		10392	12846
Ensembl ID		ENSG00000213066	ENSG00000198221
Uniprot IDs		A0A087WV25 B4DH64 O95684
PDB IDs		2D68
Enriched GO Terms of Interacting Partners?		Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Ribonuclease T2 Activity N-acetylglucosamine Kinase Activity Muramyl Dipeptide Kinase Activity	Negative Regulation Of Cortisol Secretion Negative Regulation Of Growth Hormone Secretion Non-membrane Spanning Protein Tyrosine Phosphatase Activity Negative Regulation Of Neutrophil Activation Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Atrioventricular Canal Development Microvillus Organization Negative Regulation Of Glucocorticoid Secretion Regulation Of Neutrophil Activation Protein Kinase Binding Peptide Hormone Receptor Binding Negative Regulation Of Cell Adhesion Mediated By Integrin Bergmann Glial Cell Differentiation Intestinal Epithelial Cell Migration Neutrophil Activation Involved In Immune Response Cerebellar Cortex Formation Protein Tyrosine Kinase Inhibitor Activity Regulation Of Growth Hormone Secretion Neurotrophin TRK Receptor Signaling Pathway Insulin Receptor Binding Peptidyl-tyrosine Dephosphorylation Platelet Formation Positive Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of Chondrocyte Differentiation Positive Regulation Of Cellular Response To Insulin Stimulus Megakaryocyte Development Microtubule Anchoring Genitalia Development Regulation Of Type I Interferon-mediated Signaling Pathway Protein Tyrosine Kinase Binding Positive Regulation Of Interferon-beta Production Neurotrophin Signaling Pathway Negative Regulation Of Insulin Secretion Signaling Receptor Complex Adaptor Activity Astrocyte Differentiation Phosphotyrosine Residue Binding Cellular Response To Epidermal Growth Factor Stimulus Regulation Of Protein Export From Nucleus Positive Regulation Of D-glucose Import Positive Regulation Of D-glucose Transmembrane Transport Face Morphogenesis T Cell Costimulation Homeostasis Of Number Of Cells Within A Tissue Cell Projection Organization Negative Regulation Of Type I Interferon Production Platelet-derived Growth Factor Receptor Signaling Pathway Regulation Of Lipopolysaccharide-mediated Signaling Pathway Negative Regulation Of Peptide Secretion Negative Regulation Of Lipid Transport Epithelial Cell Migration
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