ASCC3 and ASCC1

Number of citations of the paper that reports this interaction (PMID 12077347)
15

Data Source:
HPRD (two hybrid, in vivo)

		ASCC3	ASCC1
Gene Name		activating signal cointegrator 1 complex subunit 3	activating signal cointegrator 1 complex subunit 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Intracellular Nucleus Cytoplasm Golgi Apparatus Membrane	Transcription Factor Complex Cytoplasm
	Molecular Function	Protein Binding ATP Binding ATP-dependent 3'-5' DNA Helicase Activity Poly(A) RNA Binding	RNA Binding
	Biological Process	DNA Dealkylation Involved In DNA Repair Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Proliferation DNA Duplex Unwinding	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Economic and political preferences (immigration/crime) ( 22566634)
Protein-Protein Interactions		6 interactors: ASCC1 JUN RELA SKIL SRF TRIP4	6 interactors: ASCC3 JUN NCOA6 RELA SRF TRAF2
Entrez ID		10973	51008
HPRD ID		09980	12497
Ensembl ID		ENSG00000112249
Uniprot IDs		Q8N3C0	B3KU20 Q8N9N2
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Response To Cytokine Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Cell Differentiation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Blastocyst Formation Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Aging Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Nucleobase-containing Compound Metabolic Process Epithelium Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Toll-like Receptor 5 Signaling Pathway Biosynthetic Process Toll-like Receptor 10 Signaling Pathway Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Cellular Nitrogen Compound Metabolic Process Toll-like Receptor 9 Signaling Pathway Positive Regulation Of Neurogenesis TRIF-dependent Toll-like Receptor Signaling Pathway Response To Nutrient Levels MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Response To Extracellular Stimulus Positive Regulation Of Axonogenesis Nitrogen Compound Metabolic Process Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Cell Development Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Generation Of Neurons Contractile Actin Filament Bundle Assembly Cellular Response To Potassium Ion Starvation Acetaldehyde Metabolic Process Regulation Of Cell Differentiation Cellular Response To Growth Factor Stimulus	Cellular Response To Stress TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Toll-like Receptor 4 Signaling Pathway Toll-like Receptor Signaling Pathway Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response Response To Reactive Oxygen Species Response To Stress Response To Cytokine Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Innate Immune Response Myeloid Cell Differentiation Transcription From RNA Polymerase II Promoter Immune System Process NIK/NF-kappaB Signaling Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Aging Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Response To Organic Substance Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Response To Oxidative Stress Response To Nutrient Levels MyD88-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Response To Extracellular Stimulus Immune Response-regulating Signaling Pathway Response To Inorganic Substance Blood Vessel Development Heart Development Positive Regulation Of Macromolecule Biosynthetic Process Vasculature Development Positive Regulation Of Gene Expression
Tagcloud ?		53bp1 activating alkb alkbh3 alkylated alkylation cointegrator collaborates correlates crucial dealkylation demethylation dioxygenases encodes foci helicase integrity largest maintain methylcytosine nucleotides overexpressed ph2a preferentially purification represents stranded whose	877c accrued ancestry barrett ccnd1 concordant counseling cthrc1 decades derivation discordant eac esophagus germline integrating interrogation lysate mapped msr1 multiplatform mutated pairs predisposition premorbid priority prospectively r293x sibling validation
Tagcloud (Difference) ?		53bp1 activating alkb alkbh3 alkylated alkylation cointegrator collaborates correlates crucial dealkylation demethylation dioxygenases encodes foci helicase integrity largest maintain methylcytosine nucleotides overexpressed ph2a preferentially purification represents stranded whose	877c accrued ancestry barrett ccnd1 concordant counseling cthrc1 decades derivation discordant eac esophagus germline integrating interrogation lysate mapped msr1 multiplatform mutated pairs predisposition premorbid priority prospectively r293x sibling validation
Tagcloud (Intersection) ?