SMPDL3A and BRINP1

Number of citations of the paper that reports this interaction (PMID 12442002)
7

Data Source:
HPRD (in vivo, in vitro, two hybrid)

		SMPDL3A	BRINP1
Gene Name		sphingomyelin phosphodiesterase, acid-like 3A	bone morphogenetic protein/retinoic acid inducible neural-specific 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Extracellular Vesicular Exosome	Cytoplasm
	Molecular Function	Sphingomyelin Phosphodiesterase Activity Protein Binding Hydrolase Activity, Acting On Glycosyl Bonds	Protein Binding
	Biological Process	Sphingomyelin Catabolic Process Biological_process	Cell Cycle Arrest Cell Death Positive Regulation Of Neuron Differentiation Negative Regulation Of Cell Cycle Negative Regulation Of Mitotic Cell Cycle Cellular Response To Retinoic Acid
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: BRINP1	5 interactors: CCND1 HDAC3 MDM2 RAC1 SMPDL3A
Entrez ID		10924	1620
HPRD ID		10244	04181
Ensembl ID		ENSG00000172594	ENSG00000078725
Uniprot IDs		B7Z729 Q92484	O60477
PDB IDs
Enriched GO Terms of Interacting Partners?			Response To Magnesium Ion Negative Regulation Of Cell Cycle Arrest Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Response To Iron Ion Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Mitotic Cell Cycle Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Negative Regulation Of Cell Cycle Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Cellular Response To Growth Factor Stimulus Response To Growth Factor Regulation Of Cell Cycle Arrest Mitotic DNA Damage Checkpoint Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Mitotic DNA Integrity Checkpoint Cellular Response To Organic Substance Response To Vitamin Positive Regulation Of Nucleocytoplasmic Transport Cellular Response To UV-C Cellular Response To Vitamin B1 Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Protein Phosphorylation Regulation Of G1/S Transition Of Mitotic Cell Cycle Response To UV Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Protein Stability Notch Signaling Pathway Regulation Of Protein Metabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Embryonic Olfactory Bulb Interneuron Precursor Migration Negative Regulation Of Interleukin-23 Production DNA Damage Checkpoint Positive Regulation Of Intracellular Protein Transport Positive Regulation Of Phosphorylation Mitotic Cell Cycle Checkpoint Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process Regulation Of Cell Cycle Re-entry Into Mitotic Cell Cycle Engulfment Of Apoptotic Cell Response To Organic Substance Positive Regulation Of Cellular Metabolic Process
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