ARPP19 and SPDYC

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ARPP19	SPDYC
Description		cAMP regulated phosphoprotein 19	speedy/RINGO cell cycle regulator family member C
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm	Nucleus Cytoplasm
	Molecular Function	Protein Phosphatase Inhibitor Activity Signaling Receptor Binding Protein Binding Potassium Channel Regulator Activity Phosphatase Inhibitor Activity Protein Phosphatase Regulator Activity Protein Phosphatase 2A Binding	Protein Binding Protein Kinase Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Positive Regulation Of Gluconeogenesis Positive Regulation Of D-glucose Import Cell Division
Pathways		MASTL Facilitates Mitotic Progression MASTL Facilitates Mitotic Progression
Drugs
Diseases
GWAS		Blood protein levels ( 30072576)
Interacting Genes		4 interacting genes: APP IKBKG SNCA SPDYC	4 interacting genes: ARPP19 FCF1 LZTS1 PAX6
Entrez ID		10776	387778
HPRD ID		09264	17367
Ensembl ID		ENSG00000128989	ENSG00000204710
Uniprot IDs		H3BMD8 P56211	Q5MJ68
PDB IDs		8TTB
Enriched GO Terms of Interacting Partners?		Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Presynapse Organization Response To Copper Ion Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Presynapse Assembly Amyloid Fibril Formation Regulation Of Neurotransmitter Uptake Microglial Cell Activation Leukocyte Activation Involved In Inflammatory Response Cellular Response To Copper Ion Regulation Of Neuronal Synaptic Plasticity Enzyme Binding Amyloid-beta Complex Response To Interleukin-1 Growth Cone Lamellipodium Adult Locomotory Behavior Regulation Of Response To Calcium Ion Macrophage Activation Amylin Binding Protein Tetramerization Positive Regulation Of Toll Signaling Pathway Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Reactive Oxygen Species Metabolic Process Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of Catabolic Process Establishment Of Vesicle Localization Acetylcholine Receptor Activator Activity PTB Domain Binding Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Calcium Ion Transmembrane Transport Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Endosome To Plasma Membrane Transport Vesicle Adult Behavior Positive Regulation Of Endothelin Production Positive Regulation Of Endocytosis Regulation Of Reactive Oxygen Species Metabolic Process Growth Cone Filopodium Growth Cone Positive Regulation Of Synaptic Transmission Positive Regulation Of Small Molecule Metabolic Process Protein-containing Complex Lipoprotein Particle Myeloid Leukocyte Activation Import Into Cell Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway	Forebrain Dorsal/ventral Pattern Formation Regulation Of Asymmetric Cell Division Forebrain-midbrain Boundary Formation Type B Pancreatic Cell Differentiation Pancreatic A Cell Development Forebrain Neuron Fate Commitment Habenula Development Oligodendrocyte Cell Fate Specification Ventral Spinal Cord Development Cornea Development In Camera-type Eye Pallium Development Salivary Gland Morphogenesis Formation Of Anatomical Boundary Iris Morphogenesis Glial Cell Fate Specification Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain Cerebral Cortex Regionalization Lacrimal Gland Development Telencephalon Regionalization Phosphatase Inhibitor Activity Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage In 5'-ETS Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Dorsal/ventral Axis Specification HMG Box Domain Binding Co-SMAD Binding Regulation Of Timing Of Cell Differentiation Regulation Of Development, Heterochronic Negative Regulation Of Neuroblast Proliferation Embryonic Camera-type Eye Morphogenesis Enteroendocrine Cell Differentiation
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