ATP5MG and CEP164

		ATP5MG	CEP164
Description		ATP synthase membrane subunit g	centrosomal protein 164
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Proton-transporting ATP Synthase Complex	Extracellular Space Nucleus Nucleoplasm Cytoplasm Centrosome Centriole Cytosol Cytoskeleton Ciliary Transition Fiber
	Molecular Function	Protein Binding Proton Transmembrane Transporter Activity Proton-transporting ATP Synthase Activity, Rotational Mechanism	Protein Binding
	Biological Process	ATP Biosynthetic Process Monoatomic Ion Transport Proton Motive Force-driven ATP Synthesis Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport	DNA Repair DNA Damage Response Cell Projection Organization Cell Division Cilium Assembly
Pathways		Formation of ATP by chemiosmotic coupling Cristae formation Mitochondrial protein degradation	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2
Drugs		Artenimol Phenethyl Isothiocyanate
Diseases
GWAS			Apolipoprotein A1 levels ( 32203549) Diastolic blood pressure ( 30578418) Diffusing capacity of carbon monoxide ( 30694715) Hematocrit ( 32888494) Hemoglobin levels ( 32327693) Hippocampal volume in Alzheimer's disease dementia ( 29274321) Metabolite levels ( 23823483) Pulse pressure ( 27841878 28135244 30578418)
Interacting Genes		2 interacting genes: MAGEC1 RHOU	6 interacting genes: ATR ATRIP CLP1 MAPK14 UBC XPA
Entrez ID		10632	22897
HPRD ID		09815	10854
Ensembl ID		ENSG00000167283	ENSG00000110274
Uniprot IDs		O75964	Q9UPV0
PDB IDs		8H9F 8H9J 8H9M 8H9Q 8H9S 8H9T 8H9U 8H9V 8KHF 8KI3	7NWJ 7O06 7O0S 7O3B
Enriched GO Terms of Interacting Partners?			ATR-ATRIP Complex Cellular Response To UV Cellular Response To Light Stimulus DNA Damage Checkpoint Signaling Response To UV Signal Transduction In Response To DNA Damage Cellular Response To Radiation Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cell Cycle Phase Transition DNA Damage Response Negative Regulation Of Cell Cycle Process Response To Light Stimulus Negative Regulation Of Cell Cycle Cellular Response To Ionizing Radiation Nucleic Acid Metabolic Process Nucleotide-excision Repair, DNA Damage Recognition Response To Radiation Regulation Of Cell Cycle Phase Transition Establishment Of Protein-containing Complex Localization To Telomere Nucleoplasm Establishment Of RNA Localization To Telomere Positive Regulation Of Telomerase Catalytic Core Complex Assembly Nucleotide-excision Repair Involved In Interstrand Cross-link Repair ATP-dependent Polyribonucleotide 5'-hydroxyl-kinase Activity Polynucleotide 5'-hydroxyl-kinase Activity ATP-dependent Polynucleotide 5'-hydroxyl-kinase Activity DNA Repair Histone H2AXS139 Kinase Activity Regulation Of Synaptic Membrane Adhesion Nucleotide-excision Repair Factor 1 Complex Global Gene Silencing By MRNA Cleavage Kinase Activity Response To Ionizing Radiation Regulation Of Double-strand Break Repair TRNA-intron Endonuclease Complex ATP-dependent Polydeoxyribonucleotide 5'-hydroxyl-kinase Activity Cellular Response To Stress DNA Metabolic Process Regulation Of Cell Cycle Process NFAT Protein Binding MRNA Cleavage Factor Complex Response To Mechanical Stimulus MutSalpha Complex Binding Macromolecule Metabolic Process MutLalpha Complex Binding Mitogen-activated Protein Kinase P38 Binding Stress-induced Premature Senescence Cerebellar Cortex Development Intracellular Signal Transduction NLRP1 Inflammasome Complex Assembly
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