CRISP3 and MSMB

Number of citations of the paper that reports this interaction (PubMedID 35063506)
62

Data Source:
BioGRID (pull down)

		CRISP3	MSMB
Description		cysteine rich secretory protein 3	microseminoprotein beta
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Matrix Specific Granule Lumen Specific Granule Tertiary Granule Lumen	Extracellular Region Extracellular Space Nucleus
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Defense Response Sexual Reproduction Innate Immune Response
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS			Blood protein levels ( 30072576) Mean corpuscular hemoglobin ( 20139978) Mean corpuscular volume ( 20139978) PCA3 expression level ( 23555189) Prostate cancer ( 18264097 31562322 31226226 26443449 25939597 24753544 21743057 20676098 18264096) Prostate cancer (early onset) ( 24740154) Prostate-specific antigen levels ( 25434496 23269536 28139693) Serum prostate-specific antigen levels ( 21160077)
Interacting Genes		3 interacting genes: A1BG GPR152 MSMB	3 interacting genes: APP CRISP3 SGTA
Entrez ID		10321	4477
HPRD ID		11788	01143
Ensembl ID		ENSG00000096006	ENSG00000263639
Uniprot IDs		J3KPA1 P54108	P08118
PDB IDs			2IZ3 3IX0
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Proteolysis Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Protein Catabolic Process Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Response To Endoplasmic Reticulum Stress Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization TRC Complex Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling BAT3 Complex Binding Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Negative Regulation Of ERAD Pathway Regulation Of Protein Catabolic Process Heparan Sulfate Binding Signaling Receptor Activator Activity Regulation Of Proteolysis Peptidase Activator Activity Cellular Response To Manganese Ion Antifungal Humoral Response Nuclear Envelope Lumen Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation
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