MAEA and GID8

Number of citations of the paper that reports this interaction (PMID 17467196)
20

Data Source:
BioGRID (pull down)

		MAEA	GID8
Gene Name		macrophage erythroblast attacher	GID complex subunit 8
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Spindle Actomyosin Contractile Ring Cytoskeleton Integral Component Of Plasma Membrane Nuclear Matrix	Nucleoplasm Cell Junction
	Molecular Function	Actin Binding
	Biological Process	Cytoskeleton Organization Cell Cycle Cell Adhesion Regulation Of Mitotic Cell Cycle Negative Regulation Of Myeloid Cell Apoptotic Process Erythrocyte Maturation Enucleate Erythrocyte Development Cell Division
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661) Type 2 diabetes ( 22158537)
Protein-Protein Interactions		2 interactors: GID8 MYOC	3 interactors: MAEA MKLN1 RMND5A
Entrez ID		10296	54994
HPRD ID		08427	12738
Ensembl ID		ENSG00000090316
Uniprot IDs		B4DQT1 B4DVN3 D6RIB6 Q7L5Y9	Q9NWU2
PDB IDs
Enriched GO Terms of Interacting Partners?		Skeletal Muscle Hypertrophy ERBB2-ERBB3 Signaling Pathway ERBB2 Signaling Pathway Non-canonical Wnt Signaling Pathway Via JNK Cascade Non-canonical Wnt Signaling Pathway Via MAPK Cascade Clustering Of Voltage-gated Sodium Channels Skeletal Muscle Adaptation Positive Regulation Of Mitochondrial Depolarization Negative Regulation Of Stress Fiber Assembly Neuronal Ion Channel Clustering Negative Regulation Of Actin Filament Bundle Assembly Regulation Of Mitochondrial Depolarization Negative Regulation Of Rho Protein Signal Transduction Positive Regulation Of Focal Adhesion Assembly Positive Regulation Of Adherens Junction Organization Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Muscle Hypertrophy Neuron Maturation Non-canonical Wnt Signaling Pathway Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Membrane Depolarization Negative Regulation Of Cell-matrix Adhesion Positive Regulation Of Stress Fiber Assembly Myelination In Peripheral Nervous System Regulation Of Focal Adhesion Assembly Positive Regulation Of Actin Filament Bundle Assembly Schwann Cell Development Negative Regulation Of Cell-substrate Adhesion Positive Regulation Of Cell-matrix Adhesion Negative Regulation Of Ras Protein Signal Transduction Regulation Of Cell Junction Assembly Negative Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Stress Fiber Assembly Schwann Cell Differentiation Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Positive Regulation Of Protein Kinase B Signaling Regulation Of Phosphatidylinositol 3-kinase Signaling Glial Cell Development Peripheral Nervous System Development Regulation Of Cell-matrix Adhesion Positive Regulation Of Cell-substrate Adhesion Regulation Of Protein Kinase B Signaling Osteoblast Differentiation Cell Maturation Myelination Axon Ensheathment Regulation Of Ion Homeostasis Negative Regulation Of Cytoskeleton Organization Positive Regulation Of Cell Morphogenesis Involved In Differentiation ERBB Signaling Pathway	Enucleate Erythrocyte Development Enucleate Erythrocyte Differentiation Erythrocyte Maturation Negative Regulation Of Myeloid Cell Apoptotic Process Cytoskeleton Organization Cell Adhesion Regulation Of Myeloid Cell Apoptotic Process Erythrocyte Development Actin Cytoskeleton Reorganization Erythrocyte Differentiation Erythrocyte Homeostasis Myeloid Cell Homeostasis Cell Maturation
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